Siderovski DP - Search Results

1

Helix dipole movement and conformational variability contribute to allosteric GDP release in Galphai subunits.

Preininger AM, Funk MA, Oldham WM, Meier SM, Johnston CA, Adhikary S, Kimple AJ, Siderovski DP, Hamm HE, Iverson TM. Preininger AM, et al. Among authors: siderovski dp. Biochemistry. 2009 Mar 31;48(12):2630-42. doi: 10.1021/bi801853a. Biochemistry. 2009. PMID: 19222191 Free PMC article.

2

A direct fluorescence-based assay for RGS domain GTPase accelerating activity.

Willard FS, Kimple AJ, Johnston CA, Siderovski DP. Willard FS, et al. Among authors: siderovski dp. Anal Biochem. 2005 May 15;340(2):341-51. doi: 10.1016/j.ab.2005.02.015. Anal Biochem. 2005. PMID: 15840508

3

Fluorescence-based assays for RGS box function.

Willard FS, Kimple RJ, Kimple AJ, Johnston CA, Siderovski DP. Willard FS, et al. Among authors: siderovski dp. Methods Enzymol. 2004;389:56-71. doi: 10.1016/S0076-6879(04)89004-9. Methods Enzymol. 2004. PMID: 15313559 Review.

4

A bifunctional Galphai/Galphas modulatory peptide that attenuates adenylyl cyclase activity.

Johnston CA, Ramer JK, Blaesius R, Fredericks Z, Watts VJ, Siderovski DP. Johnston CA, et al. Among authors: siderovski dp. FEBS Lett. 2005 Oct 24;579(25):5746-50. doi: 10.1016/j.febslet.2005.09.059. FEBS Lett. 2005. PMID: 16225870 Free PMC article.

5

Minimal determinants for binding activated G alpha from the structure of a G alpha(i1)-peptide dimer.

Johnston CA, Lobanova ES, Shavkunov AS, Low J, Ramer JK, Blaesius R, Fredericks Z, Willard FS, Kuhlman B, Arshavsky VY, Siderovski DP. Johnston CA, et al. Among authors: siderovski dp. Biochemistry. 2006 Sep 26;45(38):11390-400. doi: 10.1021/bi0613832. Biochemistry. 2006. PMID: 16981699 Free PMC article.

6

Structural basis for nucleotide exchange on G alpha i subunits and receptor coupling specificity.

Johnston CA, Siderovski DP. Johnston CA, et al. Among authors: siderovski dp. Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):2001-6. doi: 10.1073/pnas.0608599104. Epub 2007 Jan 30. Proc Natl Acad Sci U S A. 2007. Retraction in: Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1808. doi: 10.1073/pnas.1200173109 PMID: 17264214 Free PMC article. Retracted.

7

Receptor-mediated activation of heterotrimeric G-proteins: current structural insights.

Johnston CA, Siderovski DP. Johnston CA, et al. Among authors: siderovski dp. Mol Pharmacol. 2007 Aug;72(2):219-30. doi: 10.1124/mol.107.034348. Epub 2007 Apr 12. Mol Pharmacol. 2007. PMID: 17430994 Review.

8

Structure of the parathyroid hormone receptor C terminus bound to the G-protein dimer Gbeta1gamma2.

Johnston CA, Kimple AJ, Giguère PM, Siderovski DP. Johnston CA, et al. Among authors: siderovski dp. Structure. 2008 Jul;16(7):1086-94. doi: 10.1016/j.str.2008.04.010. Structure. 2008. Retraction in: Structure. 2011 Aug 10;19(8):1200. doi: 10.1016/j.str.2011.07.010 PMID: 18611381 Free PMC article. Retracted.

9

A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics.

Willard FS, Zheng Z, Guo J, Digby GJ, Kimple AJ, Conley JM, Johnston CA, Bosch D, Willard MD, Watts VJ, Lambert NA, Ikeda SR, Du Q, Siderovski DP. Willard FS, et al. Among authors: siderovski dp. J Biol Chem. 2008 Dec 26;283(52):36698-710. doi: 10.1074/jbc.M804936200. Epub 2008 Nov 4. J Biol Chem. 2008. PMID: 18984596 Free PMC article.

10

A homogeneous method to measure nucleotide exchange by α-subunits of heterotrimeric G-proteins using fluorescence polarization.

Muller RE, Klein KR, Hutsell SQ, Siderovski DP, Kimple AJ. Muller RE, et al. Among authors: siderovski dp. Assay Drug Dev Technol. 2010 Oct;8(5):621-4. doi: 10.1089/adt.2010.0286. Epub 2010 Jul 27. Assay Drug Dev Technol. 2010. PMID: 20662737 Free PMC article.

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