McNiff PA - Search Results

1

Octahydrophenanthrene-2,7-diol analogues as dissociated glucocorticoid receptor agonists: discovery and lead exploration.

Robinson RP, Buckbinder L, Haugeto AI, McNiff PA, Millham ML, Reese MR, Schaefer JF, Abramov YA, Bordner J, Chantigny YA, Kleinman EF, Laird ER, Morgan BP, Murray JC, Salter ED, Wessel MD, Yocum SA. Robinson RP, et al. Among authors: mcniff pa. J Med Chem. 2009 Mar 26;52(6):1731-43. doi: 10.1021/jm801512v. J Med Chem. 2009. PMID: 19239259

2

2-Aryl-3-methyloctahydrophenanthrene-2,3,7-triols as potent dissociated glucocorticoid receptor agonists.

Chantigny YA, Murray JC, Kleinman EF, Robinson RP, Plotkin MA, Reese MR, Buckbinder L, McNiff PA, Millham ML, Schaefer JF, Abramov YA, Bordner J. Chantigny YA, et al. Among authors: mcniff pa. J Med Chem. 2015 Mar 26;58(6):2658-77. doi: 10.1021/jm501601b. Epub 2015 Mar 17. J Med Chem. 2015. PMID: 25706100

3

Reduction of intracellular pH by tenidap. Involvement of cellular anion transporters in the pH change.

McNiff P, Robinson RP, Gabel CA. McNiff P, et al. Biochem Pharmacol. 1995 Oct 26;50(9):1421-32. doi: 10.1016/0006-2952(95)02034-9. Biochem Pharmacol. 1995. PMID: 7503793

4

Quantitative structure-activity relationships of antitumor guanidinothiazolecarboxamides with survival enhancement for therapy in the 3LL Lewis lung carcinoma model.

Schnur RC, Gallaschun RJ, Singleton DH, Grissom M, Sloan DE, Goodwin P, McNiff PA, Fliri AF, Mangano FM, Olson TH, et al. Schnur RC, et al. Among authors: mcniff pa. J Med Chem. 1991 Jul;34(7):1975-82. doi: 10.1021/jm00111a009. J Med Chem. 1991. PMID: 2066970

5

Inhibition of cytokine activation processes in vitro by tenidap, a novel anti-inflammatory agent.

McNiff PA, Laliberte RE, Svensson L, Pazoles CJ, Gabel CA. McNiff PA, et al. Cytokine. 1995 Feb;7(2):196-208. doi: 10.1006/cyto.1995.1027. Cytokine. 1995. PMID: 7780040

6

Tenidap modulates cytoplasmic pH and inhibits anion transport in vitro. I. Mechanism and evidence of functional significance.

McNiff P, Svensson L, Pazoles CJ, Gabel CA. McNiff P, et al. J Immunol. 1994 Sep 1;153(5):2180-93. J Immunol. 1994. PMID: 8051419

7

Synovial fluid from rheumatoid arthritis patients contains sufficient levels of IL-1 beta and IL-6 to promote production of serum amyloid A by Hep3B cells.

McNiff PA, Stewart C, Sullivan J, Showell HJ, Gabel CA. McNiff PA, et al. Cytokine. 1995 Feb;7(2):209-19. doi: 10.1006/cyto.1995.1028. Cytokine. 1995. PMID: 7780041 Free article.

8

LL-Z1271alpha: an interleukin-1beta production inhibitor.

Ichikawa K, Inagaki T, Kachi-Tonai H, Kojima Y, Nakamura T, Nishida H, Ueno Y, Binding P, Gabel CA, Lucas V, McNiff PA, Kojima N. Ichikawa K, et al. Among authors: mcniff pa. Biochem Biophys Res Commun. 2001 Aug 31;286(4):697-700. doi: 10.1006/bbrc.2001.5458. Biochem Biophys Res Commun. 2001. PMID: 11520053

9

Human monocyte ATP-induced IL-1 beta posttranslational processing is a dynamic process dependent on in vitro growth conditions.

Laliberte RE, Perregaux DG, McNiff P, Gabel CA. Laliberte RE, et al. J Leukoc Biol. 1997 Aug;62(2):227-39. doi: 10.1002/jlb.62.2.227. J Leukoc Biol. 1997. PMID: 9261337

10

ATP acts as an agonist to promote stimulus-induced secretion of IL-1 beta and IL-18 in human blood.

Perregaux DG, McNiff P, Laliberte R, Conklyn M, Gabel CA. Perregaux DG, et al. J Immunol. 2000 Oct 15;165(8):4615-23. doi: 10.4049/jimmunol.165.8.4615. J Immunol. 2000. PMID: 11035104

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