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Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat.
Pérez VI, Buffenstein R, Masamsetti V, Leonard S, Salmon AB, Mele J, Andziak B, Yang T, Edrey Y, Friguet B, Ward W, Richardson A, Chaudhuri A. Pérez VI, et al. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3059-64. doi: 10.1073/pnas.0809620106. Epub 2009 Feb 17. Proc Natl Acad Sci U S A. 2009. PMID: 19223593 Free PMC article.
The role of oxidative damage and stress in aging.
Bokov A, Chaudhuri A, Richardson A. Bokov A, et al. Mech Ageing Dev. 2004 Oct-Nov;125(10-11):811-26. doi: 10.1016/j.mad.2004.07.009. Mech Ageing Dev. 2004. PMID: 15541775 Review.
Overexpression of Mn superoxide dismutase does not increase life span in mice.
Jang YC, Pérez VI, Song W, Lustgarten MS, Salmon AB, Mele J, Qi W, Liu Y, Liang H, Chaudhuri A, Ikeno Y, Epstein CJ, Van Remmen H, Richardson A. Jang YC, et al. J Gerontol A Biol Sci Med Sci. 2009 Nov;64(11):1114-25. doi: 10.1093/gerona/glp100. Epub 2009 Jul 24. J Gerontol A Biol Sci Med Sci. 2009. PMID: 19633237 Free PMC article.
Reduced mitochondrial ROS, enhanced antioxidant defense, and distinct age-related changes in oxidative damage in muscles of long-lived Peromyscus leucopus.
Shi Y, Pulliam DA, Liu Y, Hamilton RT, Jernigan AL, Bhattacharya A, Sloane LB, Qi W, Chaudhuri A, Buffenstein R, Ungvari Z, Austad SN, Van Remmen H. Shi Y, et al. Am J Physiol Regul Integr Comp Physiol. 2013 Mar 1;304(5):R343-55. doi: 10.1152/ajpregu.00139.2012. Epub 2013 Jan 16. Am J Physiol Regul Integr Comp Physiol. 2013. PMID: 23325454 Free PMC article.
Superior proteome stability in the longest lived animal.
Treaster SB, Ridgway ID, Richardson CA, Gaspar MB, Chaudhuri AR, Austad SN. Treaster SB, et al. Among authors: chaudhuri ar. Age (Dordr). 2014 Jun;36(3):9597. doi: 10.1007/s11357-013-9597-9. Epub 2013 Nov 20. Age (Dordr). 2014. PMID: 24254744 Free PMC article.
66 results