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Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction.
Yu JC, Heidaran MA, Pierce JH, Gutkind JS, Lombardi D, Ruggiero M, Aaronson SA. Yu JC, et al. Among authors: gutkind js. Mol Cell Biol. 1991 Jul;11(7):3780-5. doi: 10.1128/mcb.11.7.3780-3785.1991. Mol Cell Biol. 1991. PMID: 1646396 Free PMC article.
543 results