Germino GG - Search Results

1

Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1.

Distefano G, Boca M, Rowe I, Wodarczyk C, Ma L, Piontek KB, Germino GG, Pandolfi PP, Boletta A. Distefano G, et al. Among authors: germino gg. Mol Cell Biol. 2009 May;29(9):2359-71. doi: 10.1128/MCB.01259-08. Epub 2009 Mar 2. Mol Cell Biol. 2009. PMID: 19255143 Free PMC article.

2

Polycystin: in vitro synthesis, in vivo tissue expression, and subcellular localization identifies a large membrane-associated protein.

Ibraghimov-Beskrovnaya O, Dackowski WR, Foggensteiner L, Coleman N, Thiru S, Petry LR, Burn TC, Connors TD, Van Raay T, Bradley J, Qian F, Onuchic LF, Watnick TJ, Piontek K, Hakim RM, Landes GM, Germino GG, Sandford R, Klinger KW. Ibraghimov-Beskrovnaya O, et al. Among authors: germino gg. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6397-402. doi: 10.1073/pnas.94.12.6397. Proc Natl Acad Sci U S A. 1997. PMID: 9177229 Free PMC article.

3

An unusual pattern of mutation in the duplicated portion of PKD1 is revealed by use of a novel strategy for mutation detection.

Watnick TJ, Piontek KB, Cordal TM, Weber H, Gandolph MA, Qian F, Lens XM, Neumann HP, Germino GG. Watnick TJ, et al. Among authors: germino gg. Hum Mol Genet. 1997 Sep;6(9):1473-81. doi: 10.1093/hmg/6.9.1473. Hum Mol Genet. 1997. PMID: 9285784

4

Murine Pkd1 introns 21 and 22 lack the extreme polypyrimidine bias present in human PKD1.

Piontek KB, Germino GG. Piontek KB, et al. Among authors: germino gg. Mamm Genome. 1999 Feb;10(2):194-6. doi: 10.1007/s003359900969. Mamm Genome. 1999. PMID: 9922404 No abstract available.

5

Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells.

Boletta A, Qian F, Onuchic LF, Bhunia AK, Phakdeekitcharoen B, Hanaoka K, Guggino W, Monaco L, Germino GG. Boletta A, et al. Among authors: germino gg. Mol Cell. 2000 Nov;6(5):1267-73. doi: 10.1016/s1097-2765(00)00123-4. Mol Cell. 2000. PMID: 11106764 Free article.

6

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents.

Hanaoka K, Qian F, Boletta A, Bhunia AK, Piontek K, Tsiokas L, Sukhatme VP, Guggino WB, Germino GG. Hanaoka K, et al. Among authors: germino gg. Nature. 2000 Dec 21-28;408(6815):990-4. doi: 10.1038/35050128. Nature. 2000. PMID: 11140688

7

Biochemical characterization of bona fide polycystin-1 in vitro and in vivo.

Boletta A, Qian F, Onuchic LF, Bragonzi A, Cortese M, Deen PM, Courtoy PJ, Soria MR, Devuyst O, Monaco L, Germino GG. Boletta A, et al. Among authors: germino gg. Am J Kidney Dis. 2001 Dec;38(6):1421-9. doi: 10.1053/ajkd.2001.29282. Am J Kidney Dis. 2001. PMID: 11728985

8

PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2.

Bhunia AK, Piontek K, Boletta A, Liu L, Qian F, Xu PN, Germino FJ, Germino GG. Bhunia AK, et al. Among authors: germino fj, germino gg. Cell. 2002 Apr 19;109(2):157-68. doi: 10.1016/s0092-8674(02)00716-x. Cell. 2002. PMID: 12007403 Free article.

9

Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.

Qian F, Boletta A, Bhunia AK, Xu H, Liu L, Ahrabi AK, Watnick TJ, Zhou F, Germino GG. Qian F, et al. Among authors: germino gg. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16981-6. doi: 10.1073/pnas.252484899. Epub 2002 Dec 13. Proc Natl Acad Sci U S A. 2002. PMID: 12482949 Free PMC article.

10

Role of polycystins in renal tubulogenesis.

Boletta A, Germino GG. Boletta A, et al. Among authors: germino gg. Trends Cell Biol. 2003 Sep;13(9):484-92. doi: 10.1016/s0962-8924(03)00169-7. Trends Cell Biol. 2003. PMID: 12946628 Review.

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