Brookes S - Search Results

1

Functional, structural, and genetic evaluation of 20 CDKN2A germ line mutations identified in melanoma-prone families or patients.

Kannengiesser C, Brookes S, del Arroyo AG, Pham D, Bombled J, Barrois M, Mauffret O, Avril MF, Chompret A, Lenoir GM, Sarasin A; French Hereditary Melanoma Study Group; Peters G, Bressac-de Paillerets B. Kannengiesser C, et al. Among authors: brookes s. Hum Mutat. 2009 Apr;30(4):564-74. doi: 10.1002/humu.20845. Hum Mutat. 2009. PMID: 19260062

2

Functional evaluation of tumour-specific variants of p16INK4a/CDKN2A: correlation with protein structure information.

Ruas M, Brookes S, McDonald NQ, Peters G. Ruas M, et al. Among authors: brookes s. Oncogene. 1999 Sep 23;18(39):5423-34. doi: 10.1038/sj.onc.1202918. Oncogene. 1999. PMID: 10498896

3

Two p16 (CDKN2A) germline mutations in 30 Israeli melanoma families.

Yakobson E, Shemesh P, Azizi E, Winkler E, Lassam N, Hogg D, Brookes S, Peters G, Lotem M, Zlotogorski A, Landau M, Safro M, Shafir R, Friedman E, Peretz H. Yakobson E, et al. Among authors: brookes s. Eur J Hum Genet. 2000 Aug;8(8):590-6. doi: 10.1038/sj.ejhg.5200505. Eur J Hum Genet. 2000. PMID: 10951521

4

Germline mutations of the CDKN2 gene in UK melanoma families.

Harland M, Meloni R, Gruis N, Pinney E, Brookes S, Spurr NK, Frischauf AM, Bataille V, Peters G, Cuzick J, Selby P, Bishop DT, Bishop JN. Harland M, et al. Among authors: brookes s. Hum Mol Genet. 1997 Nov;6(12):2061-7. doi: 10.1093/hmg/6.12.2061. Hum Mol Genet. 1997. PMID: 9328469

5

A CDKN2A mutation in familial melanoma that abrogates binding of p16INK4a to CDK4 but not CDK6.

Jones R, Ruas M, Gregory F, Moulin S, Delia D, Manoukian S, Rowe J, Brookes S, Peters G. Jones R, et al. Among authors: brookes s. Cancer Res. 2007 Oct 1;67(19):9134-41. doi: 10.1158/0008-5472.CAN-07-1528. Cancer Res. 2007. PMID: 17909018

6

Contribution of p16(INK4a) to replicative senescence of human fibroblasts.

Brookes S, Rowe J, Gutierrez Del Arroyo A, Bond J, Peters G. Brookes S, et al. Exp Cell Res. 2004 Aug 15;298(2):549-59. doi: 10.1016/j.yexcr.2004.04.035. Exp Cell Res. 2004. PMID: 15265701

7

CDK4 and CDK6 delay senescence by kinase-dependent and p16INK4a-independent mechanisms.

Ruas M, Gregory F, Jones R, Poolman R, Starborg M, Rowe J, Brookes S, Peters G. Ruas M, et al. Among authors: brookes s. Mol Cell Biol. 2007 Jun;27(12):4273-82. doi: 10.1128/MCB.02286-06. Epub 2007 Apr 9. Mol Cell Biol. 2007. PMID: 17420273 Free PMC article.

8

The significance of p16INK4a in cell defenses against transformation.

Drayton S, Brookes S, Rowe J, Peters G. Drayton S, et al. Among authors: brookes s. Cell Cycle. 2004 May;3(5):611-5. Epub 2004 May 9. Cell Cycle. 2004. PMID: 15044857 Review.

9

Contrasting behavior of the p18INK4c and p16INK4a tumor suppressors in both replicative and oncogene-induced senescence.

Gagrica S, Brookes S, Anderton E, Rowe J, Peters G. Gagrica S, et al. Among authors: brookes s. Cancer Res. 2012 Jan 1;72(1):165-75. doi: 10.1158/0008-5472.CAN-11-2552. Epub 2011 Nov 11. Cancer Res. 2012. PMID: 22080569 Free PMC article.

10

Evidence for a CDK4-dependent checkpoint in a conditional model of cellular senescence.

Brookes S, Gagrica S, Sanij E, Rowe J, Gregory FJ, Hara E, Peters G. Brookes S, et al. Cell Cycle. 2015;14(8):1164-73. doi: 10.1080/15384101.2015.1010866. Cell Cycle. 2015. PMID: 25695870 Free PMC article.

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