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pp32 (ANP32A) expression inhibits pancreatic cancer cell growth and induces gemcitabine resistance by disrupting HuR binding to mRNAs.
Williams TK, Costantino CL, Bildzukewicz NA, Richards NG, Rittenhouse DW, Einstein L, Cozzitorto JA, Keen JC, Dasgupta A, Gorospe M, Gonye GE, Yeo CJ, Witkiewicz AK, Brody JR. Williams TK, et al. Among authors: costantino cl. PLoS One. 2010 Nov 29;5(11):e15455. doi: 10.1371/journal.pone.0015455. PLoS One. 2010. PMID: 21152064 Free PMC article.
Limits to thymidylate synthase and TP53 genes as predictive determinants for fluoropyrimidine sensitivity and further evidence for RNA-based toxicity as a major influence.
Brody JR, Hucl T, Costantino CL, Eshleman JR, Gallmeier E, Zhu H, van der Heijden MS, Winter JM, Wikiewicz AK, Yeo CJ, Kern SE. Brody JR, et al. Among authors: costantino cl. Cancer Res. 2009 Feb 1;69(3):984-91. doi: 10.1158/0008-5472.CAN-08-3610. Epub 2009 Jan 20. Cancer Res. 2009. PMID: 19155291 Free PMC article.
28 results