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Ca2+/calmodulin-dependent kinase II triggers cell membrane injury by inducing complement factor B gene expression in the mouse heart.
Singh MV, Kapoun A, Higgins L, Kutschke W, Thurman JM, Zhang R, Singh M, Yang J, Guan X, Lowe JS, Weiss RM, Zimmermann K, Yull FE, Blackwell TS, Mohler PJ, Anderson ME. Singh MV, et al. Among authors: zhang r. J Clin Invest. 2009 Apr;119(4):986-96. doi: 10.1172/JCI35814. Epub 2009 Mar 9. J Clin Invest. 2009. PMID: 19273909 Free PMC article.
Death, cardiac dysfunction, and arrhythmias are increased by calmodulin kinase II in calcineurin cardiomyopathy.
Khoo MS, Li J, Singh MV, Yang Y, Kannankeril P, Wu Y, Grueter CE, Guan X, Oddis CV, Zhang R, Mendes L, Ni G, Madu EC, Yang J, Bass M, Gomez RJ, Wadzinski BE, Olson EN, Colbran RJ, Anderson ME. Khoo MS, et al. Among authors: zhang r. Circulation. 2006 Sep 26;114(13):1352-9. doi: 10.1161/CIRCULATIONAHA.106.644583. Epub 2006 Sep 18. Circulation. 2006. PMID: 16982937
Calmodulin kinase II inhibition protects against myocardial cell apoptosis in vivo.
Yang Y, Zhu WZ, Joiner ML, Zhang R, Oddis CV, Hou Y, Yang J, Price EE, Gleaves L, Eren M, Ni G, Vaughan DE, Xiao RP, Anderson ME. Yang Y, et al. Among authors: zhang r. Am J Physiol Heart Circ Physiol. 2006 Dec;291(6):H3065-75. doi: 10.1152/ajpheart.00353.2006. Epub 2006 Jul 21. Am J Physiol Heart Circ Physiol. 2006. PMID: 16861697 Free article.
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