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Muramyl dipeptide enhances osteoclast formation induced by lipopolysaccharide, IL-1 alpha, and TNF-alpha through nucleotide-binding oligomerization domain 2-mediated signaling in osteoblasts.
Yang S, Takahashi N, Yamashita T, Sato N, Takahashi M, Mogi M, Uematsu T, Kobayashi Y, Nakamichi Y, Takeda K, Akira S, Takada H, Udagawa N, Furusawa K. Yang S, et al. Among authors: kobayashi y. J Immunol. 2005 Aug 1;175(3):1956-64. doi: 10.4049/jimmunol.175.3.1956. J Immunol. 2005. PMID: 16034140
Prostaglandin E2 strongly inhibits human osteoclast formation.
Take I, Kobayashi Y, Yamamoto Y, Tsuboi H, Ochi T, Uematsu S, Okafuji N, Kurihara S, Udagawa N, Takahashi N. Take I, et al. Among authors: kobayashi y. Endocrinology. 2005 Dec;146(12):5204-14. doi: 10.1210/en.2005-0451. Epub 2005 Sep 8. Endocrinology. 2005. PMID: 16150915
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