Warne T - Search Results

1

Development and crystallization of a minimal thermostabilised G protein-coupled receptor.

Warne T, Serrano-Vega MJ, Tate CG, Schertler GF. Warne T, et al. Protein Expr Purif. 2009 Jun;65(2):204-13. doi: 10.1016/j.pep.2009.01.014. Protein Expr Purif. 2009. PMID: 19297694

2

Expression and purification of truncated, non-glycosylated turkey beta-adrenergic receptors for crystallization.

Warne T, Chirnside J, Schertler GF. Warne T, et al. Biochim Biophys Acta. 2003 Feb 17;1610(1):133-40. doi: 10.1016/s0005-2736(02)00716-2. Biochim Biophys Acta. 2003. PMID: 12586387 Free article.

3

Structure of a beta1-adrenergic G-protein-coupled receptor.

Warne T, Serrano-Vega MJ, Baker JG, Moukhametzianov R, Edwards PC, Henderson R, Leslie AG, Tate CG, Schertler GF. Warne T, et al. Nature. 2008 Jul 24;454(7203):486-91. doi: 10.1038/nature07101. Epub 2008 Jun 25. Nature. 2008. PMID: 18594507 Free PMC article.

4

The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor.

Warne T, Moukhametzianov R, Baker JG, Nehmé R, Edwards PC, Leslie AG, Schertler GF, Tate CG. Warne T, et al. Nature. 2011 Jan 13;469(7329):241-4. doi: 10.1038/nature09746. Nature. 2011. PMID: 21228877 Free PMC article.

5

Two distinct conformations of helix 6 observed in antagonist-bound structures of a beta1-adrenergic receptor.

Moukhametzianov R, Warne T, Edwards PC, Serrano-Vega MJ, Leslie AG, Tate CG, Schertler GF. Moukhametzianov R, et al. Among authors: warne t. Proc Natl Acad Sci U S A. 2011 May 17;108(20):8228-32. doi: 10.1073/pnas.1100185108. Epub 2011 May 3. Proc Natl Acad Sci U S A. 2011. PMID: 21540331 Free PMC article.

6

Ligand occupancy in crystal structure of β1-adrenergic G protein-coupled receptor.

Leslie AG, Warne T, Tate CG. Leslie AG, et al. Among authors: warne t. Nat Struct Mol Biol. 2015 Dec;22(12):941-2. doi: 10.1038/nsmb.3130. Nat Struct Mol Biol. 2015. PMID: 26643842 Free PMC article. No abstract available.

7

The Escherichia coli multidrug transporter EmrE is a dimer in the detergent-solubilised state.

Butler PJ, Ubarretxena-Belandia I, Warne T, Tate CG. Butler PJ, et al. Among authors: warne t. J Mol Biol. 2004 Jul 16;340(4):797-808. doi: 10.1016/j.jmb.2004.05.014. J Mol Biol. 2004. PMID: 15223321

8

Agonist-bound structures of G protein-coupled receptors.

Lebon G, Warne T, Tate CG. Lebon G, et al. Among authors: warne t. Curr Opin Struct Biol. 2012 Aug;22(4):482-90. doi: 10.1016/j.sbi.2012.03.007. Epub 2012 Apr 3. Curr Opin Struct Biol. 2012. PMID: 22480933 Review.

9

Crystal structures of a stabilized β1-adrenoceptor bound to the biased agonists bucindolol and carvedilol.

Warne T, Edwards PC, Leslie AG, Tate CG. Warne T, et al. Structure. 2012 May 9;20(5):841-9. doi: 10.1016/j.str.2012.03.014. Structure. 2012. PMID: 22579251 Free PMC article.

10

The importance of interactions with helix 5 in determining the efficacy of β-adrenoceptor ligands.

Warne T, Tate CG. Warne T, et al. Biochem Soc Trans. 2013 Feb 1;41(1):159-65. doi: 10.1042/BST20120228. Biochem Soc Trans. 2013. PMID: 23356277 Review.

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