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A Runx2 threshold for the cleidocranial dysplasia phenotype.
Lou Y, Javed A, Hussain S, Colby J, Frederick D, Pratap J, Xie R, Gaur T, van Wijnen AJ, Jones SN, Stein GS, Lian JB, Stein JL. Lou Y, et al. Among authors: hussain s. Hum Mol Genet. 2009 Feb 1;18(3):556-68. doi: 10.1093/hmg/ddn383. Epub 2008 Nov 20. Hum Mol Genet. 2009. PMID: 19028669 Free PMC article.
Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse.
Gaur T, Hussain S, Mudhasani R, Parulkar I, Colby JL, Frederick D, Kream BE, van Wijnen AJ, Stein JL, Stein GS, Jones SN, Lian JB. Gaur T, et al. Among authors: hussain s. Dev Biol. 2010 Apr 1;340(1):10-21. doi: 10.1016/j.ydbio.2010.01.008. Epub 2010 Jan 15. Dev Biol. 2010. PMID: 20079730 Free PMC article.
A proteasome inhibitor, bortezomib, inhibits breast cancer growth and reduces osteolysis by downregulating metastatic genes.
Jones MD, Liu JC, Barthel TK, Hussain S, Lovria E, Cheng D, Schoonmaker JA, Mulay S, Ayers DC, Bouxsein ML, Stein GS, Mukherjee S, Lian JB. Jones MD, et al. Among authors: hussain s. Clin Cancer Res. 2010 Oct 15;16(20):4978-89. doi: 10.1158/1078-0432.CCR-09-3293. Epub 2010 Sep 15. Clin Cancer Res. 2010. PMID: 20843837 Free PMC article.
The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss.
Pratap J, Akech J, Wixted JJ, Szabo G, Hussain S, McGee-Lawrence ME, Li X, Bedard K, Dhillon RJ, van Wijnen AJ, Stein JL, Stein GS, Westendorf JJ, Lian JB. Pratap J, et al. Among authors: hussain s. Mol Cancer Ther. 2010 Dec;9(12):3210-20. doi: 10.1158/1535-7163.MCT-10-0572. Mol Cancer Ther. 2010. PMID: 21159607 Free PMC article.
6,214 results