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N6-Cycloalkyl- and N6-bicycloalkyl-C5'(C2')-modified adenosine derivatives as high-affinity and selective agonists at the human A1 adenosine receptor with antinociceptive effects in mice.
Franchetti P, Cappellacci L, Vita P, Petrelli R, Lavecchia A, Kachler S, Klotz KN, Marabese I, Luongo L, Maione S, Grifantini M. Franchetti P, et al. Among authors: luongo l. J Med Chem. 2009 Apr 23;52(8):2393-406. doi: 10.1021/jm801456g. J Med Chem. 2009. PMID: 19317449
The analgesic effect of N-arachidonoyl-serotonin, a FAAH inhibitor and TRPV1 receptor antagonist, associated with changes in rostral ventromedial medulla and locus coeruleus cell activity in rats.
de Novellis V, Palazzo E, Rossi F, De Petrocellis L, Petrosino S, Guida F, Luongo L, Migliozzi A, Cristino L, Marabese I, Starowicz K, Di Marzo V, Maione S; Endocannabinoid Research Group. de Novellis V, et al. Among authors: luongo l. Neuropharmacology. 2008 Dec;55(7):1105-13. doi: 10.1016/j.neuropharm.2008.06.023. Epub 2008 Jun 20. Neuropharmacology. 2008. PMID: 18616956
Intraperiaqueductal gray glycine and D-serine exert dual effects on rostral ventromedial medulla ON- and OFF-cell activity and thermoceptive threshold in the rat.
Palazzo E, Guida F, Migliozzi A, Gatta L, Marabese I, Luongo L, Rossi C, de Novellis V, Fernández-Sánchez E, Soukupova M, Zafra F, Maione S. Palazzo E, et al. Among authors: luongo l. J Neurophysiol. 2009 Dec;102(6):3169-79. doi: 10.1152/jn.00124.2009. Epub 2009 Sep 23. J Neurophysiol. 2009. PMID: 19776366 Free article.
Investigations on the 4-quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands.
Pasquini S, Ligresti A, Mugnaini C, Semeraro T, Cicione L, De Rosa M, Guida F, Luongo L, De Chiaro M, Cascio MG, Bolognini D, Marini P, Pertwee R, Maione S, Di Marzo V, Corelli F. Pasquini S, et al. Among authors: luongo l. J Med Chem. 2010 Aug 26;53(16):5915-28. doi: 10.1021/jm100123x. J Med Chem. 2010. PMID: 20718492
185 results