Kokubu A - Search Results

1

Vandetanib (ZD6474), an inhibitor of VEGFR and EGFR signalling, as a novel molecular-targeted therapy against cholangiocarcinoma.

Yoshikawa D, Ojima H, Kokubu A, Ochiya T, Kasai S, Hirohashi S, Shibata T. Yoshikawa D, et al. Among authors: kokubu a. Br J Cancer. 2009 Apr 21;100(8):1257-66. doi: 10.1038/sj.bjc.6604988. Epub 2009 Mar 24. Br J Cancer. 2009. PMID: 19319137 Free PMC article.

2

Prognostic significance of overexpression of c-Met oncoprotein in cholangiocarcinoma.

Miyamoto M, Ojima H, Iwasaki M, Shimizu H, Kokubu A, Hiraoka N, Kosuge T, Yoshikawa D, Kono T, Furukawa H, Shibata T. Miyamoto M, et al. Among authors: kokubu a. Br J Cancer. 2011 Jun 28;105(1):131-8. doi: 10.1038/bjc.2011.199. Epub 2011 Jun 14. Br J Cancer. 2011. PMID: 21673683 Free PMC article.

3

Gene expression profiling of epidermal growth factor receptor/KRAS pathway activation in lung adenocarcinoma.

Shibata T, Hanada S, Kokubu A, Matsuno Y, Asamura H, Ohta T, Sakamoto M, Hirohashi S. Shibata T, et al. Among authors: kokubu a. Cancer Sci. 2007 Jul;98(7):985-91. doi: 10.1111/j.1349-7006.2007.00483.x. Epub 2007 Apr 23. Cancer Sci. 2007. PMID: 17459062 Free PMC article.

4

Oncogenic mutation of PIK3CA in small cell lung carcinoma: a potential therapeutic target pathway for chemotherapy-resistant lung cancer.

Shibata T, Kokubu A, Tsuta K, Hirohashi S. Shibata T, et al. Among authors: kokubu a. Cancer Lett. 2009 Oct 8;283(2):203-11. doi: 10.1016/j.canlet.2009.03.038. Epub 2009 Apr 25. Cancer Lett. 2009. PMID: 19394761

5

Global downstream pathway analysis reveals a dependence of oncogenic NF-E2-related factor 2 mutation on the mTOR growth signaling pathway.

Shibata T, Saito S, Kokubu A, Suzuki T, Yamamoto M, Hirohashi S. Shibata T, et al. Among authors: kokubu a. Cancer Res. 2010 Nov 15;70(22):9095-105. doi: 10.1158/0008-5472.CAN-10-0384. Epub 2010 Nov 9. Cancer Res. 2010. PMID: 21062981

6

Mutations of the epidermal growth factor receptor gene in atypical adenomatous hyperplasia and bronchioloalveolar carcinoma of the lung.

Yoshida Y, Shibata T, Kokubu A, Tsuta K, Matsuno Y, Kanai Y, Asamura H, Tsuchiya R, Hirohashi S. Yoshida Y, et al. Among authors: kokubu a. Lung Cancer. 2005 Oct;50(1):1-8. doi: 10.1016/j.lungcan.2005.04.012. Lung Cancer. 2005. PMID: 15950315

7

Genetic classification of lung adenocarcinoma based on array-based comparative genomic hybridization analysis: its association with clinicopathologic features.

Shibata T, Uryu S, Kokubu A, Hosoda F, Ohki M, Sakiyama T, Matsuno Y, Tsuchiya R, Kanai Y, Kondo T, Imoto I, Inazawa J, Hirohashi S. Shibata T, et al. Among authors: kokubu a. Clin Cancer Res. 2005 Sep 1;11(17):6177-85. doi: 10.1158/1078-0432.CCR-05-0293. Clin Cancer Res. 2005. PMID: 16144918

8

Genetic inactivation of the APC gene contributes to the malignant progression of sporadic hepatocellular carcinoma: a case report.

Katoh H, Shibata T, Kokubu A, Ojima H, Kosuge T, Kanai Y, Hirohashi S. Katoh H, et al. Among authors: kokubu a. Genes Chromosomes Cancer. 2006 Nov;45(11):1050-7. doi: 10.1002/gcc.20362. Genes Chromosomes Cancer. 2006. PMID: 16897741

9

Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer.

Shibata T, Kokubu A, Gotoh M, Ojima H, Ohta T, Yamamoto M, Hirohashi S. Shibata T, et al. Among authors: kokubu a. Gastroenterology. 2008 Oct;135(4):1358-1368, 1368.e1-4. doi: 10.1053/j.gastro.2008.06.082. Epub 2008 Jul 3. Gastroenterology. 2008. PMID: 18692501

10

Establishment of six new human biliary tract carcinoma cell lines and identification of MAGEH1 as a candidate biomarker for predicting the efficacy of gemcitabine treatment.

Ojima H, Yoshikawa D, Ino Y, Shimizu H, Miyamoto M, Kokubu A, Hiraoka N, Morofuji N, Kondo T, Onaya H, Okusaka T, Shimada K, Sakamoto Y, Esaki M, Nara S, Kosuge T, Hirohashi S, Kanai Y, Shibata T. Ojima H, et al. Among authors: kokubu a. Cancer Sci. 2010 Apr;101(4):882-8. doi: 10.1111/j.1349-7006.2009.01462.x. Epub 2009 Dec 8. Cancer Sci. 2010. PMID: 20088962 Free PMC article.

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