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Plasma adrenomedullin and endothelin-1 levels are reduced and Raynaud's phenomenon improved by daily tadalafil administration in male patients with systemic sclerosis.
Rosato E, Letizia C, Proietti M, Aversa A, Menghi G, Rossi C, Torella E, Cotesta D, Petramala L, Bruzziches R, Spera G, Pisarri S, Salsano F. Rosato E, et al. Among authors: torella e. J Biol Regul Homeost Agents. 2009 Jan-Mar;23(1):23-9. J Biol Regul Homeost Agents. 2009. PMID: 19321043 Clinical Trial.