Kruczynski A - Search Results

1

Antitumor activity of pyridoisoquinoline derivatives F91873 and F91874, novel multikinase inhibitors with activity against the anaplastic lymphoma kinase.

Kruczynski A, Mayer P, Marchand A, Vispé S, Fournier E, Annereau JP, Brel V, Barret JM, Delsol G, Imbert T, Fahy J, Bailly C. Kruczynski A, et al. Anticancer Drugs. 2009 Jun;20(5):364-72. doi: 10.1097/CAD.0b013e32832a2ed9. Anticancer Drugs. 2009. PMID: 19322071

2

Antitumor pharmacology -- quo vadis?

Bailly C, Barret JM, Kruczynski A. Bailly C, et al. Among authors: kruczynski a. Curr Med Chem Anticancer Agents. 2004 Sep;4(5):389-91. doi: 10.2174/1568011043352849. Curr Med Chem Anticancer Agents. 2004. PMID: 15379689 Review.

3

F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system.

Barret JM, Kruczynski A, Vispé S, Annereau JP, Brel V, Guminski Y, Delcros JG, Lansiaux A, Guilbaud N, Imbert T, Bailly C. Barret JM, et al. Among authors: kruczynski a. Cancer Res. 2008 Dec 1;68(23):9845-53. doi: 10.1158/0008-5472.CAN-08-2748. Cancer Res. 2008. PMID: 19047165

4

Anaplastic lymphoma kinase as a therapeutic target.

Kruczynski A, Delsol G, Laurent C, Brousset P, Lamant L. Kruczynski A, et al. Expert Opin Ther Targets. 2012 Nov;16(11):1127-38. doi: 10.1517/14728222.2012.719498. Epub 2012 Sep 24. Expert Opin Ther Targets. 2012. PMID: 22998583 Review.

5

Synergistic effects of F 11782, a novel dual inhibitor of topoisomerases I and II, in combination with other anticancer agents.

Barret JM, Kruczynski A, Etiévant C, Hill BT. Barret JM, et al. Among authors: kruczynski a. Cancer Chemother Pharmacol. 2002 Jun;49(6):479-86. doi: 10.1007/s00280-002-0451-5. Epub 2002 Apr 6. Cancer Chemother Pharmacol. 2002. PMID: 12107553

6

Novel aspects of natural and modified vinca alkaloids.

Duflos A, Kruczynski A, Barret JM. Duflos A, et al. Among authors: kruczynski a. Curr Med Chem Anticancer Agents. 2002 Jan;2(1):55-70. doi: 10.2174/1568011023354452. Curr Med Chem Anticancer Agents. 2002. PMID: 12678751 Review.

7

Physalin B, a novel inhibitor of the ubiquitin-proteasome pathway, triggers NOXA-associated apoptosis.

Vandenberghe I, Créancier L, Vispé S, Annereau JP, Barret JM, Pouny I, Samson A, Aussagues Y, Massiot G, Ausseil F, Bailly C, Kruczynski A. Vandenberghe I, et al. Among authors: kruczynski a. Biochem Pharmacol. 2008 Aug 15;76(4):453-62. doi: 10.1016/j.bcp.2008.05.031. Epub 2008 Jun 4. Biochem Pharmacol. 2008. PMID: 18577376

8

Preclinical activity of F14512, designed to target tumors expressing an active polyamine transport system.

Kruczynski A, Vandenberghe I, Pillon A, Pesnel S, Goetsch L, Barret JM, Guminski Y, Le Pape A, Imbert T, Bailly C, Guilbaud N. Kruczynski A, et al. Invest New Drugs. 2011 Feb;29(1):9-21. doi: 10.1007/s10637-009-9328-3. Epub 2009 Sep 24. Invest New Drugs. 2011. PMID: 19777159

9

Cytotoxicity and cell death mechanisms induced by the polyamine-vectorized anti-cancer drug F14512 targeting topoisomerase II.

Brel V, Annereau JP, Vispé S, Kruczynski A, Bailly C, Guilbaud N. Brel V, et al. Among authors: kruczynski a. Biochem Pharmacol. 2011 Dec 15;82(12):1843-52. doi: 10.1016/j.bcp.2011.08.028. Epub 2011 Sep 8. Biochem Pharmacol. 2011. PMID: 21924246

10

F14512, a polyamine-vectorized inhibitor of topoisomerase II, exhibits a marked anti-tumor activity in ovarian cancer.

Thibault B, Clement E, Zorza G, Meignan S, Delord JP, Couderc B, Bailly C, Narducci F, Vandenberghe I, Kruczynski A, Guilbaud N, Ferré P, Annereau JP. Thibault B, et al. Among authors: kruczynski a. Cancer Lett. 2016 Jan 1;370(1):10-8. doi: 10.1016/j.canlet.2015.09.006. Epub 2015 Sep 25. Cancer Lett. 2016. PMID: 26404751

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