Hasty P - Search Results

1

Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells.

Li H, Choi YJ, Hanes MA, Marple T, Vogel H, Hasty P. Li H, et al. Among authors: hasty p. Oncogene. 2009 Apr 23;28(16):1875-8. doi: 10.1038/onc.2009.57. Epub 2009 Mar 30. Oncogene. 2009. PMID: 19330025

2

Deletion of Ku86 causes early onset of senescence in mice.

Vogel H, Lim DS, Karsenty G, Finegold M, Hasty P. Vogel H, et al. Among authors: hasty p. Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10770-5. doi: 10.1073/pnas.96.19.10770. Proc Natl Acad Sci U S A. 1999. PMID: 10485901 Free PMC article.

3

Analysis of ku80-mutant mice and cells with deficient levels of p53.

Lim DS, Vogel H, Willerford DM, Sands AT, Platt KA, Hasty P. Lim DS, et al. Among authors: hasty p. Mol Cell Biol. 2000 Jun;20(11):3772-80. doi: 10.1128/MCB.20.11.3772-3780.2000. Mol Cell Biol. 2000. PMID: 10805721 Free PMC article.

4

The impact energy metabolism and genome maintenance have on longevity and senescence: lessons from yeast to mammals.

Hasty P. Hasty P. Mech Ageing Dev. 2001 Oct;122(15):1651-62. doi: 10.1016/s0047-6374(01)00294-9. Mech Ageing Dev. 2001. PMID: 11557271 Review.

5

Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice.

Donoho G, Brenneman MA, Cui TX, Donoviel D, Vogel H, Goodwin EH, Chen DJ, Hasty P. Donoho G, et al. Among authors: hasty p. Genes Chromosomes Cancer. 2003 Apr;36(4):317-31. doi: 10.1002/gcc.10148. Genes Chromosomes Cancer. 2003. PMID: 12619154

6

A genotoxic screen: rapid analysis of cellular dose-response to a wide range of agents that either damage DNA or alter genome maintenance pathways.

Marple T, Li H, Hasty P. Marple T, et al. Among authors: hasty p. Mutat Res. 2004 Oct 4;554(1-2):253-66. doi: 10.1016/j.mrfmmm.2004.05.004. Mutat Res. 2004. PMID: 15450423

7

Non-homologous end joining, but not homologous recombination, enables survival for cells exposed to a histone deacetylase inhibitor.

Yaneva M, Li H, Marple T, Hasty P. Yaneva M, et al. Among authors: hasty p. Nucleic Acids Res. 2005 Sep 21;33(16):5320-30. doi: 10.1093/nar/gki821. Print 2005. Nucleic Acids Res. 2005. PMID: 16177181 Free PMC article.

8

Ku80 and p53 suppress medulloblastoma that arise independent of Rag-1-induced DSBs.

Holcomb VB, Vogel H, Marple T, Kornegay RW, Hasty P. Holcomb VB, et al. Among authors: hasty p. Oncogene. 2006 Nov 16;25(54):7159-65. doi: 10.1038/sj.onc.1209704. Epub 2006 Jun 5. Oncogene. 2006. PMID: 16751807

9

Embryonic stem cells deficient for Brca2 or Blm exhibit divergent genotoxic profiles that support opposing activities during homologous recombination.

Marple T, Kim TM, Hasty P. Marple T, et al. Among authors: hasty p. Mutat Res. 2006 Dec 1;602(1-2):110-20. doi: 10.1016/j.mrfmmm.2006.08.005. Epub 2006 Sep 25. Mutat Res. 2006. PMID: 16997331

10

Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer.

Li H, Vogel H, Holcomb VB, Gu Y, Hasty P. Li H, et al. Among authors: hasty p. Mol Cell Biol. 2007 Dec;27(23):8205-14. doi: 10.1128/MCB.00785-07. Epub 2007 Sep 17. Mol Cell Biol. 2007. PMID: 17875923 Free PMC article.

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