Vogel H - Search Results

1

Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells.

Li H, Choi YJ, Hanes MA, Marple T, Vogel H, Hasty P. Li H, et al. Among authors: vogel h. Oncogene. 2009 Apr 23;28(16):1875-8. doi: 10.1038/onc.2009.57. Epub 2009 Mar 30. Oncogene. 2009. PMID: 19330025

2

Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer.

Li H, Vogel H, Holcomb VB, Gu Y, Hasty P. Li H, et al. Among authors: vogel h. Mol Cell Biol. 2007 Dec;27(23):8205-14. doi: 10.1128/MCB.00785-07. Epub 2007 Sep 17. Mol Cell Biol. 2007. PMID: 17875923 Free PMC article.

3

Deletion of Ku80 causes early aging independent of chronic inflammation and Rag-1-induced DSBs.

Holcomb VB, Vogel H, Hasty P. Holcomb VB, et al. Among authors: vogel h. Mech Ageing Dev. 2007 Nov-Dec;128(11-12):601-8. doi: 10.1016/j.mad.2007.08.006. Epub 2007 Sep 12. Mech Ageing Dev. 2007. PMID: 17928034 Free PMC article.

4

Ku80 deletion suppresses spontaneous tumors and induces a p53-mediated DNA damage response.

Holcomb VB, Rodier F, Choi Y, Busuttil RA, Vogel H, Vijg J, Campisi J, Hasty P. Holcomb VB, et al. Among authors: vogel h. Cancer Res. 2008 Nov 15;68(22):9497-502. doi: 10.1158/0008-5472.CAN-08-2085. Cancer Res. 2008. PMID: 19010925 Free PMC article.

5

Unlike p53, p27 failed to exhibit an anti-tumor genetic interaction with Ku80.

Holcomb VB, Vogel H, Hasty P. Holcomb VB, et al. Among authors: vogel h. Cell Cycle. 2009 Aug;8(15):2463-6. doi: 10.4161/cc.8.15.9249. Epub 2009 Aug 11. Cell Cycle. 2009. PMID: 19597334

6

Ku80 and p53 suppress medulloblastoma that arise independent of Rag-1-induced DSBs.

Holcomb VB, Vogel H, Marple T, Kornegay RW, Hasty P. Holcomb VB, et al. Among authors: vogel h. Oncogene. 2006 Nov 16;25(54):7159-65. doi: 10.1038/sj.onc.1209704. Epub 2006 Jun 5. Oncogene. 2006. PMID: 16751807

7

Analysis of ku80-mutant mice and cells with deficient levels of p53.

Lim DS, Vogel H, Willerford DM, Sands AT, Platt KA, Hasty P. Lim DS, et al. Among authors: vogel h. Mol Cell Biol. 2000 Jun;20(11):3772-80. doi: 10.1128/MCB.20.11.3772-3780.2000. Mol Cell Biol. 2000. PMID: 10805721 Free PMC article.

8

Deletion of Ku86 causes early onset of senescence in mice.

Vogel H, Lim DS, Karsenty G, Finegold M, Hasty P. Vogel H, et al. Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10770-5. doi: 10.1073/pnas.96.19.10770. Proc Natl Acad Sci U S A. 1999. PMID: 10485901 Free PMC article.

9

Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice.

Donoho G, Brenneman MA, Cui TX, Donoviel D, Vogel H, Goodwin EH, Chen DJ, Hasty P. Donoho G, et al. Among authors: vogel h. Genes Chromosomes Cancer. 2003 Apr;36(4):317-31. doi: 10.1002/gcc.10148. Genes Chromosomes Cancer. 2003. PMID: 12619154

10

A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice.

Harvey M, Vogel H, Morris D, Bradley A, Bernstein A, Donehower LA. Harvey M, et al. Among authors: vogel h. Nat Genet. 1995 Mar;9(3):305-11. doi: 10.1038/ng0395-305. Nat Genet. 1995. PMID: 7773294

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