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The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions.
Montanier C, Money VA, Pires VM, Flint JE, Pinheiro BA, Goyal A, Prates JA, Izumi A, Stålbrand H, Morland C, Cartmell A, Kolenova K, Topakas E, Dodson EJ, Bolam DN, Davies GJ, Fontes CM, Gilbert HJ. Montanier C, et al. Among authors: gilbert hj. PLoS Biol. 2009 Mar 31;7(3):e71. doi: 10.1371/journal.pbio.1000071. PLoS Biol. 2009. PMID: 19338387 Free PMC article.
Circular permutation provides an evolutionary link between two families of calcium-dependent carbohydrate binding modules.
Montanier C, Flint JE, Bolam DN, Xie H, Liu Z, Rogowski A, Weiner DP, Ratnaparkhe S, Nurizzo D, Roberts SM, Turkenburg JP, Davies GJ, Gilbert HJ. Montanier C, et al. Among authors: gilbert hj. J Biol Chem. 2010 Oct 8;285(41):31742-54. doi: 10.1074/jbc.M110.142133. Epub 2010 Jul 21. J Biol Chem. 2010. PMID: 20659893 Free PMC article.
Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function.
Montanier C, van Bueren AL, Dumon C, Flint JE, Correia MA, Prates JA, Firbank SJ, Lewis RJ, Grondin GG, Ghinet MG, Gloster TM, Herve C, Knox JP, Talbot BG, Turkenburg JP, Kerovuo J, Brzezinski R, Fontes CM, Davies GJ, Boraston AB, Gilbert HJ. Montanier C, et al. Among authors: gilbert hj. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3065-70. doi: 10.1073/pnas.0808972106. Epub 2009 Feb 13. Proc Natl Acad Sci U S A. 2009. PMID: 19218457 Free PMC article.
Understanding how diverse beta-mannanases recognize heterogeneous substrates.
Tailford LE, Ducros VM, Flint JE, Roberts SM, Morland C, Zechel DL, Smith N, Bjørnvad ME, Borchert TV, Wilson KS, Davies GJ, Gilbert HJ. Tailford LE, et al. Among authors: gilbert hj. Biochemistry. 2009 Jul 28;48(29):7009-18. doi: 10.1021/bi900515d. Biochemistry. 2009. PMID: 19441796
293 results