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The cyclin-dependent kinase inhibitor roscovitine and the nucleoside analog sangivamycin induce apoptosis in caspase-3 deficient breast cancer cells independent of caspase mediated P-glycoprotein cleavage: implications for therapy of drug resistant breast cancers.
Cappellini A, Chiarini F, Ognibene A, McCubrey JA, Martelli AM. Cappellini A, et al. Among authors: ognibene a. Cell Cycle. 2009 May 1;8(9):1421-5. doi: 10.4161/cc.8.9.8323. Epub 2009 May 2. Cell Cycle. 2009. PMID: 19342873 Free PMC article.
Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against T-cell acute lymphoblastic leukemia.
Chiarini F, Grimaldi C, Ricci F, Tazzari PL, Evangelisti C, Ognibene A, Battistelli M, Falcieri E, Melchionda F, Pession A, Pagliaro P, McCubrey JA, Martelli AM. Chiarini F, et al. Among authors: ognibene a. Cancer Res. 2010 Oct 15;70(20):8097-107. doi: 10.1158/0008-5472.CAN-10-1814. Epub 2010 Sep 28. Cancer Res. 2010. PMID: 20876803
A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemia.
Chiarini F, Lonetti A, Teti G, Orsini E, Bressanin D, Cappellini A, Ricci F, Tazzari PL, Ognibene A, Falconi M, Pagliaro P, Iacobucci I, Martinelli G, Amadori S, McCubrey JA, Martelli AM. Chiarini F, et al. Among authors: ognibene a. Oncotarget. 2012 Dec;3(12):1615-28. doi: 10.18632/oncotarget.762. Oncotarget. 2012. PMID: 23271044 Free PMC article.
Nuclear phosphoinositides and their roles in cell biology and disease.
Martelli AM, Ognibene A, Buontempo F, Fini M, Bressanin D, Goto K, McCubrey JA, Cocco L, Evangelisti C. Martelli AM, et al. Among authors: ognibene a. Crit Rev Biochem Mol Biol. 2011 Oct;46(5):436-57. doi: 10.3109/10409238.2011.609530. Epub 2011 Sep 14. Crit Rev Biochem Mol Biol. 2011. PMID: 21913876
168 results