Botrugno OA - Search Results

1

Histone deacetylase inhibitors as a new weapon in the arsenal of differentiation therapies of cancer.

Botrugno OA, Santoro F, Minucci S. Botrugno OA, et al. Cancer Lett. 2009 Aug 8;280(2):134-44. doi: 10.1016/j.canlet.2009.02.027. Epub 2009 Apr 2. Cancer Lett. 2009. PMID: 19345000 Review.

2

Molecular pathways: old drugs define new pathways: non-histone acetylation at the crossroads of the DNA damage response and autophagy.

Botrugno OA, Robert T, Vanoli F, Foiani M, Minucci S. Botrugno OA, et al. Clin Cancer Res. 2012 May 1;18(9):2436-42. doi: 10.1158/1078-0432.CCR-11-0767. Epub 2012 Apr 18. Clin Cancer Res. 2012. PMID: 22512979

3

A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance.

Santoro F, Botrugno OA, Dal Zuffo R, Pallavicini I, Matthews GM, Cluse L, Barozzi I, Senese S, Fornasari L, Moretti S, Altucci L, Pelicci PG, Chiocca S, Johnstone RW, Minucci S. Santoro F, et al. Among authors: botrugno oa. Blood. 2013 Apr 25;121(17):3459-68. doi: 10.1182/blood-2012-10-461988. Epub 2013 Feb 25. Blood. 2013. PMID: 23440245 Free article.

4

HDAC3 activity is required for initiation of leukemogenesis in acute promyelocytic leukemia.

Mehdipour P, Santoro F, Botrugno OA, Romanenghi M, Pagliuca C, Matthews GM, Johnstone RW, Minucci S. Mehdipour P, et al. Among authors: botrugno oa. Leukemia. 2017 Apr;31(4):995-997. doi: 10.1038/leu.2017.3. Epub 2017 Jan 24. Leukemia. 2017. PMID: 28074065 No abstract available.

5

Recruitment of the histone methyltransferase SUV39H1 and its role in the oncogenic properties of the leukemia-associated PML-retinoic acid receptor fusion protein.

Carbone R, Botrugno OA, Ronzoni S, Insinga A, Di Croce L, Pelicci PG, Minucci S. Carbone R, et al. Among authors: botrugno oa. Mol Cell Biol. 2006 Feb;26(4):1288-96. doi: 10.1128/MCB.26.4.1288-1296.2006. Mol Cell Biol. 2006. PMID: 16449642 Free PMC article.

6

Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2.

Binda C, Valente S, Romanenghi M, Pilotto S, Cirilli R, Karytinos A, Ciossani G, Botrugno OA, Forneris F, Tardugno M, Edmondson DE, Minucci S, Mattevi A, Mai A. Binda C, et al. Among authors: botrugno oa. J Am Chem Soc. 2010 May 19;132(19):6827-33. doi: 10.1021/ja101557k. J Am Chem Soc. 2010. PMID: 20415477

7

Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer.

Di Micco R, Sulli G, Dobreva M, Liontos M, Botrugno OA, Gargiulo G, dal Zuffo R, Matti V, d'Ario G, Montani E, Mercurio C, Hahn WC, Gorgoulis V, Minucci S, d'Adda di Fagagna F. Di Micco R, et al. Among authors: botrugno oa. Nat Cell Biol. 2011 Mar;13(3):292-302. doi: 10.1038/ncb2170. Epub 2011 Feb 20. Nat Cell Biol. 2011. PMID: 21336312 Free PMC article.

8

HDACs link the DNA damage response, processing of double-strand breaks and autophagy.

Robert T, Vanoli F, Chiolo I, Shubassi G, Bernstein KA, Rothstein R, Botrugno OA, Parazzoli D, Oldani A, Minucci S, Foiani M. Robert T, et al. Among authors: botrugno oa. Nature. 2011 Mar 3;471(7336):74-79. doi: 10.1038/nature09803. Nature. 2011. PMID: 21368826 Free PMC article.

9

The DNA demethylating agent decitabine activates the TRAIL pathway and induces apoptosis in acute myeloid leukemia.

Soncini M, Santoro F, Gutierrez A, Frigè G, Romanenghi M, Botrugno OA, Pallavicini I, Pelicci P, Di Croce L, Minucci S. Soncini M, et al. Among authors: botrugno oa. Biochim Biophys Acta. 2013 Jan;1832(1):114-20. doi: 10.1016/j.bbadis.2012.10.001. Epub 2012 Oct 6. Biochim Biophys Acta. 2013. PMID: 23046813 Free article.

10

Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A.

Vianello P, Botrugno OA, Cappa A, Ciossani G, Dessanti P, Mai A, Mattevi A, Meroni G, Minucci S, Thaler F, Tortorici M, Trifiró P, Valente S, Villa M, Varasi M, Mercurio C. Vianello P, et al. Among authors: botrugno oa. Eur J Med Chem. 2014 Oct 30;86:352-63. doi: 10.1016/j.ejmech.2014.08.068. Epub 2014 Aug 27. Eur J Med Chem. 2014. PMID: 25173853

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

33 results

Search Page

Filters