Mesecar AD - Search Results

1

Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-kappaB signaling.

Frieman M, Ratia K, Johnston RE, Mesecar AD, Baric RS. Frieman M, et al. Among authors: mesecar ad. J Virol. 2009 Jul;83(13):6689-705. doi: 10.1128/JVI.02220-08. Epub 2009 Apr 15. J Virol. 2009. PMID: 19369340 Free PMC article.

2

Proteolytic processing and deubiquitinating activity of papain-like proteases of human coronavirus NL63.

Chen Z, Wang Y, Ratia K, Mesecar AD, Wilkinson KD, Baker SC. Chen Z, et al. Among authors: mesecar ad. J Virol. 2007 Jun;81(11):6007-18. doi: 10.1128/JVI.02747-06. Epub 2007 Mar 28. J Virol. 2007. PMID: 17392370 Free PMC article.

3

Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases.

Clementz MA, Chen Z, Banach BS, Wang Y, Sun L, Ratia K, Baez-Santos YM, Wang J, Takayama J, Ghosh AK, Li K, Mesecar AD, Baker SC. Clementz MA, et al. Among authors: mesecar ad. J Virol. 2010 May;84(9):4619-29. doi: 10.1128/JVI.02406-09. Epub 2010 Feb 24. J Virol. 2010. PMID: 20181693 Free PMC article.

4

A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses.

Deng X, Agnihothram S, Mielech AM, Nichols DB, Wilson MW, StJohn SE, Larsen SD, Mesecar AD, Lenschow DJ, Baric RS, Baker SC. Deng X, et al. Among authors: mesecar ad. J Virol. 2014 Oct;88(20):11825-33. doi: 10.1128/JVI.01749-14. Epub 2014 Aug 6. J Virol. 2014. PMID: 25100850 Free PMC article.

5

Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating activity of SARS-CoV papain-like protease.

Ratia K, Kilianski A, Baez-Santos YM, Baker SC, Mesecar A. Ratia K, et al. PLoS Pathog. 2014 May 22;10(5):e1004113. doi: 10.1371/journal.ppat.1004113. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24854014 Free PMC article.

6

The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity.

Barretto N, Jukneliene D, Ratia K, Chen Z, Mesecar AD, Baker SC. Barretto N, et al. Among authors: mesecar ad. J Virol. 2005 Dec;79(24):15189-98. doi: 10.1128/JVI.79.24.15189-15198.2005. J Virol. 2005. PMID: 16306590 Free PMC article.

7

Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme.

Ratia K, Saikatendu KS, Santarsiero BD, Barretto N, Baker SC, Stevens RC, Mesecar AD. Ratia K, et al. Among authors: mesecar ad. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5717-22. doi: 10.1073/pnas.0510851103. Epub 2006 Mar 31. Proc Natl Acad Sci U S A. 2006. PMID: 16581910 Free PMC article.

8

Evaluating the 3C-like protease activity of SARS-Coronavirus: recommendations for standardized assays for drug discovery.

Grum-Tokars V, Ratia K, Begaye A, Baker SC, Mesecar AD. Grum-Tokars V, et al. Among authors: mesecar ad. Virus Res. 2008 Apr;133(1):63-73. doi: 10.1016/j.virusres.2007.02.015. Epub 2007 Mar 29. Virus Res. 2008. PMID: 17397958 Free PMC article.

9

Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein-ligand X-ray structure and biological evaluation.

Ghosh AK, Takayama J, Rao KV, Ratia K, Chaudhuri R, Mulhearn DC, Lee H, Nichols DB, Baliji S, Baker SC, Johnson ME, Mesecar AD. Ghosh AK, et al. Among authors: mesecar ad. J Med Chem. 2010 Jul 8;53(13):4968-79. doi: 10.1021/jm1004489. J Med Chem. 2010. PMID: 20527968 Free PMC article.

10

Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome-coronavirus papain-like protease.

Ghosh AK, Takayama J, Aubin Y, Ratia K, Chaudhuri R, Baez Y, Sleeman K, Coughlin M, Nichols DB, Mulhearn DC, Prabhakar BS, Baker SC, Johnson ME, Mesecar AD. Ghosh AK, et al. Among authors: mesecar ad. J Med Chem. 2009 Aug 27;52(16):5228-40. doi: 10.1021/jm900611t. J Med Chem. 2009. PMID: 19645480 Free PMC article.

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