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Mitochondrial dysfunction contributes to impaired insulin secretion in INS-1 cells with dominant-negative mutations of HNF-1alpha and in HNF-1alpha-deficient islets.
Pongratz RL, Kibbey RG, Kirkpatrick CL, Zhao X, Pontoglio M, Yaniv M, Wollheim CB, Shulman GI, Cline GW. Pongratz RL, et al. Among authors: yaniv m. J Biol Chem. 2009 Jun 19;284(25):16808-16821. doi: 10.1074/jbc.M807723200. Epub 2009 Apr 17. J Biol Chem. 2009. PMID: 19376774 Free PMC article.
Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice.
Pontoglio M, Sreenan S, Roe M, Pugh W, Ostrega D, Doyen A, Pick AJ, Baldwin A, Velho G, Froguel P, Levisetti M, Bonner-Weir S, Bell GI, Yaniv M, Polonsky KS. Pontoglio M, et al. Among authors: yaniv m. J Clin Invest. 1998 May 15;101(10):2215-22. doi: 10.1172/JCI2548. J Clin Invest. 1998. PMID: 9593777 Free PMC article.
Embryonic but not postnatal reexpression of hepatocyte nuclear factor 1alpha (HNF1alpha) can reactivate the silent phenylalanine hydroxylase gene in HNF1alpha-deficient hepatocytes.
Viollet B, Yaniv M, Pontoglio M. Viollet B, et al. Among authors: yaniv m. Mol Cell Biol. 2001 Jun;21(11):3662-70. doi: 10.1128/MCB.21.11.3662-3670.2001. Mol Cell Biol. 2001. PMID: 11340160 Free PMC article.
The failure to transcribe the phenylalanine hydroxylase (PAH) gene in the liver of hepatocyte nuclear factor 1alpha (HNF1alpha)-deficient mice correlated with DNA hypermethylation and the presence of an inactive chromatin structure (M. Pontoglio, D. M. Faust, A. Doy …
The failure to transcribe the phenylalanine hydroxylase (PAH) gene in the liver of hepatocyte nuclear factor 1alpha (HNF1alpha)-deficient mi …
HNF1alpha controls renal glucose reabsorption in mouse and man.
Pontoglio M, Prié D, Cheret C, Doyen A, Leroy C, Froguel P, Velho G, Yaniv M, Friedlander G. Pontoglio M, et al. Among authors: yaniv m. EMBO Rep. 2000 Oct;1(4):359-65. doi: 10.1093/embo-reports/kvd071. EMBO Rep. 2000. PMID: 11269503 Free PMC article.
Alpha/beta interferon differentially modulates the clearance of cytoplasmic encapsidated replication intermediates and nuclear covalently closed circular hepatitis B virus (HBV) DNA from the livers of hepatocyte nuclear factor 1alpha-null HBV transgenic mice.
Anderson AL, Banks KE, Pontoglio M, Yaniv M, McLachlan A. Anderson AL, et al. Among authors: yaniv m. J Virol. 2005 Sep;79(17):11045-52. doi: 10.1128/JVI.79.17.11045-11052.2005. J Virol. 2005. PMID: 16103155 Free PMC article.
309 results