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Page 1
Mapping adverse drug reactions in chemical space.
Scheiber J, Jenkins JL, Sukuru SC, Bender A, Mikhailov D, Milik M, Azzaoui K, Whitebread S, Hamon J, Urban L, Glick M, Davies JW. Scheiber J, et al. Among authors: sukuru sc. J Med Chem. 2009 May 14;52(9):3103-7. doi: 10.1021/jm801546k. J Med Chem. 2009. PMID: 19378990
Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications.
Maderna A, Doroski M, Subramanyam C, Porte A, Leverett CA, Vetelino BC, Chen Z, Risley H, Parris K, Pandit J, Varghese AH, Shanker S, Song C, Sukuru SC, Farley KA, Wagenaar MM, Shapiro MJ, Musto S, Lam MH, Loganzo F, O'Donnell CJ. Maderna A, et al. Among authors: sukuru sc. J Med Chem. 2014 Dec 26;57(24):10527-43. doi: 10.1021/jm501649k. Epub 2014 Dec 9. J Med Chem. 2014. PMID: 25431858
Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads.
Leverett CA, Sukuru SC, Vetelino BC, Musto S, Parris K, Pandit J, Loganzo F, Varghese AH, Bai G, Liu B, Liu D, Hudson S, Doppalapudi VR, Stock J, O'Donnell CJ, Subramanyam C. Leverett CA, et al. Among authors: sukuru sc. ACS Med Chem Lett. 2016 Aug 26;7(11):999-1004. doi: 10.1021/acsmedchemlett.6b00274. eCollection 2016 Nov 10. ACS Med Chem Lett. 2016. PMID: 27882198 Free PMC article.
Optimization of Tubulysin Antibody-Drug Conjugates: A Case Study in Addressing ADC Metabolism.
Tumey LN, Leverett CA, Vetelino B, Li F, Rago B, Han X, Loganzo F, Musto S, Bai G, Sukuru SC, Graziani EI, Puthenveetil S, Casavant J, Ratnayake A, Marquette K, Hudson S, Doppalapudi VR, Stock J, Tchistiakova L, Bessire AJ, Clark T, Lucas J, Hosselet C, O'Donnell CJ, Subramanyam C. Tumey LN, et al. Among authors: sukuru sc. ACS Med Chem Lett. 2016 Jun 22;7(11):977-982. doi: 10.1021/acsmedchemlett.6b00195. eCollection 2016 Nov 10. ACS Med Chem Lett. 2016. PMID: 27882194 Free PMC article.
12 results