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Genetic deficit of SK3 and IK1 channels disrupts the endothelium-derived hyperpolarizing factor vasodilator pathway and causes hypertension.
Brähler S, Kaistha A, Schmidt VJ, Wölfle SE, Busch C, Kaistha BP, Kacik M, Hasenau AL, Grgic I, Si H, Bond CT, Adelman JP, Wulff H, de Wit C, Hoyer J, Köhler R. Brähler S, et al. Among authors: hoyer j. Circulation. 2009 May 5;119(17):2323-32. doi: 10.1161/CIRCULATIONAHA.108.846634. Epub 2009 Apr 20. Circulation. 2009. PMID: 19380617 Free article.
Blockade of the intermediate-conductance calcium-activated potassium channel as a new therapeutic strategy for restenosis.
Köhler R, Wulff H, Eichler I, Kneifel M, Neumann D, Knorr A, Grgic I, Kämpfe D, Si H, Wibawa J, Real R, Borner K, Brakemeier S, Orzechowski HD, Reusch HP, Paul M, Chandy KG, Hoyer J. Köhler R, et al. Among authors: hoyer j. Circulation. 2003 Sep 2;108(9):1119-25. doi: 10.1161/01.CIR.0000086464.04719.DD. Epub 2003 Aug 25. Circulation. 2003. PMID: 12939222 Free article.
Impaired endothelium-derived hyperpolarizing factor-mediated dilations and increased blood pressure in mice deficient of the intermediate-conductance Ca2+-activated K+ channel.
Si H, Heyken WT, Wölfle SE, Tysiac M, Schubert R, Grgic I, Vilianovich L, Giebing G, Maier T, Gross V, Bader M, de Wit C, Hoyer J, Köhler R. Si H, et al. Among authors: hoyer j. Circ Res. 2006 Sep 1;99(5):537-44. doi: 10.1161/01.RES.0000238377.08219.0c. Epub 2006 Jul 27. Circ Res. 2006. PMID: 16873714
Renal fibrosis is attenuated by targeted disruption of KCa3.1 potassium channels.
Grgic I, Kiss E, Kaistha BP, Busch C, Kloss M, Sautter J, Müller A, Kaistha A, Schmidt C, Raman G, Wulff H, Strutz F, Gröne HJ, Köhler R, Hoyer J. Grgic I, et al. Among authors: hoyer j. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14518-23. doi: 10.1073/pnas.0903458106. Epub 2009 Aug 13. Proc Natl Acad Sci U S A. 2009. PMID: 19706538 Free PMC article.
697 results