Zhu J - Search Results

1

The structure of a receptor with two associating transmembrane domains on the cell surface: integrin alphaIIbbeta3.

Zhu J, Luo BH, Barth P, Schonbrun J, Baker D, Springer TA. Zhu J, et al. Mol Cell. 2009 Apr 24;34(2):234-49. doi: 10.1016/j.molcel.2009.02.022. Mol Cell. 2009. PMID: 19394300 Free PMC article.

2

Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling.

Zhu J, Carman CV, Kim M, Shimaoka M, Springer TA, Luo BH. Zhu J, et al. Blood. 2007 Oct 1;110(7):2475-83. doi: 10.1182/blood-2007-03-080077. Epub 2007 Jul 5. Blood. 2007. PMID: 17615290 Free PMC article.

3

Structural evidence for loose linkage between ligand binding and kinase activation in the epidermal growth factor receptor.

Lu C, Mi LZ, Grey MJ, Zhu J, Graef E, Yokoyama S, Springer TA. Lu C, et al. Among authors: zhu j. Mol Cell Biol. 2010 Nov;30(22):5432-43. doi: 10.1128/MCB.00742-10. Epub 2010 Sep 13. Mol Cell Biol. 2010. PMID: 20837704 Free PMC article.

4

Complete integrin headpiece opening in eight steps.

Zhu J, Zhu J, Springer TA. Zhu J, et al. J Cell Biol. 2013 Jun 24;201(7):1053-68. doi: 10.1083/jcb.201212037. J Cell Biol. 2013. PMID: 23798730 Free PMC article.

5

Tests of the extension and deadbolt models of integrin activation.

Zhu J, Boylan B, Luo BH, Newman PJ, Springer TA. Zhu J, et al. J Biol Chem. 2007 Apr 20;282(16):11914-20. doi: 10.1074/jbc.M700249200. Epub 2007 Feb 13. J Biol Chem. 2007. PMID: 17301049 Free PMC article.

6

Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening.

Zhu J, Zhu J, Negri A, Provasi D, Filizola M, Coller BS, Springer TA. Zhu J, et al. Blood. 2010 Dec 2;116(23):5050-9. doi: 10.1182/blood-2010-04-281154. Epub 2010 Aug 2. Blood. 2010. PMID: 20679525 Free PMC article.

7

Tests of integrin transmembrane domain homo-oligomerization during integrin ligand binding and signaling.

Wang W, Zhu J, Springer TA, Luo BH. Wang W, et al. Among authors: zhu j. J Biol Chem. 2011 Jan 21;286(3):1860-7. doi: 10.1074/jbc.M110.193797. Epub 2010 Nov 16. J Biol Chem. 2011. PMID: 21081497 Free PMC article.

8

Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS.

Zhu J, Choi WS, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D, Rasmussen M, Aster R, Thomas CJ, Filizola M, Springer TA, Coller BS. Zhu J, et al. Sci Transl Med. 2012 Mar 14;4(125):125ra32. doi: 10.1126/scitranslmed.3003576. Sci Transl Med. 2012. PMID: 22422993 Free PMC article.

9

Sequence and structure relationships within von Willebrand factor.

Zhou YF, Eng ET, Zhu J, Lu C, Walz T, Springer TA. Zhou YF, et al. Among authors: zhu j. Blood. 2012 Jul 12;120(2):449-58. doi: 10.1182/blood-2012-01-405134. Epub 2012 Apr 6. Blood. 2012. PMID: 22490677 Free PMC article.

10

Structural basis for quinine-dependent antibody binding to platelet integrin αIIbβ3.

Zhu J, Zhu J, Bougie DW, Aster RH, Springer TA. Zhu J, et al. Blood. 2015 Oct 29;126(18):2138-45. doi: 10.1182/blood-2015-04-639351. Epub 2015 Aug 17. Blood. 2015. PMID: 26282540 Free PMC article.

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