Brandt JT - Search Results

1

Cytochrome P450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes.

Mega JL, Close SL, Wiviott SD, Shen L, Hockett RD, Brandt JT, Walker JR, Antman EM, Macias WL, Braunwald E, Sabatine MS. Mega JL, et al. Among authors: brandt jt. Circulation. 2009 May 19;119(19):2553-60. doi: 10.1161/CIRCULATIONAHA.109.851949. Epub 2009 May 4. Circulation. 2009. PMID: 19414633

2

Cytochrome p-450 polymorphisms and response to clopidogrel.

Mega JL, Close SL, Wiviott SD, Shen L, Hockett RD, Brandt JT, Walker JR, Antman EM, Macias W, Braunwald E, Sabatine MS. Mega JL, et al. Among authors: brandt jt. N Engl J Med. 2009 Jan 22;360(4):354-62. doi: 10.1056/NEJMoa0809171. Epub 2008 Dec 22. N Engl J Med. 2009. PMID: 19106084 Free article.

3

Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel.

Brandt JT, Close SL, Iturria SJ, Payne CD, Farid NA, Ernest CS 2nd, Lachno DR, Salazar D, Winters KJ. Brandt JT, et al. J Thromb Haemost. 2007 Dec;5(12):2429-36. doi: 10.1111/j.1538-7836.2007.02775.x. Epub 2007 Sep 26. J Thromb Haemost. 2007. PMID: 17900275 Free article.

4

Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease.

Varenhorst C, James S, Erlinge D, Brandt JT, Braun OO, Man M, Siegbahn A, Walker J, Wallentin L, Winters KJ, Close SL. Varenhorst C, et al. Among authors: brandt jt. Eur Heart J. 2009 Jul;30(14):1744-52. doi: 10.1093/eurheartj/ehp157. Epub 2009 May 9. Eur Heart J. 2009. PMID: 19429918 Free PMC article. Clinical Trial.

5

A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation.

Brandt JT, Payne CD, Wiviott SD, Weerakkody G, Farid NA, Small DS, Jakubowski JA, Naganuma H, Winters KJ. Brandt JT, et al. Am Heart J. 2007 Jan;153(1):66.e9-16. doi: 10.1016/j.ahj.2006.10.010. Am Heart J. 2007. PMID: 17174640 Clinical Trial.

6

Cytochrome P450 3A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently.

Farid NA, Payne CD, Small DS, Winters KJ, Ernest CS 2nd, Brandt JT, Darstein C, Jakubowski JA, Salazar DE. Farid NA, et al. Among authors: brandt jt. Clin Pharmacol Ther. 2007 May;81(5):735-41. doi: 10.1038/sj.clpt.6100139. Epub 2007 Mar 14. Clin Pharmacol Ther. 2007. PMID: 17361128 Clinical Trial.

7

Prasugrel pharmacokinetics and pharmacodynamics in subjects with moderate renal impairment and end-stage renal disease.

Small DS, Wrishko RE, Ernest CS 2nd, Ni L, Winters KJ, Farid NA, Li YG, Brandt JT, Salazar DE, Borel AG, Kles KA, Payne CD. Small DS, et al. Among authors: brandt jt. J Clin Pharm Ther. 2009 Oct;34(5):585-94. doi: 10.1111/j.1365-2710.2009.01068.x. J Clin Pharm Ther. 2009. PMID: 19744014

8

Inhibition of platelet aggregation with prasugrel and clopidogrel: an integrated analysis in 846 subjects.

Li YG, Ni L, Brandt JT, Small DS, Payne CD, Ernest CS 2nd, Rohatagi S, Farid NA, Jakubowski JA, Winters KJ. Li YG, et al. Among authors: brandt jt. Platelets. 2009 Aug;20(5):316-27. doi: 10.1080/09537100903046317. Platelets. 2009. PMID: 19637095 Free article.

9

Effect of rifampin on the pharmacokinetics and pharmacodynamics of prasugrel in healthy male subjects.

Farid NA, Jakubowski JA, Payne CD, Li YG, Jin Y, Ernest II CS, Winters KJ, Brandt JT, Salazar DE, Small DS. Farid NA, et al. Among authors: brandt jt. Curr Med Res Opin. 2009 Aug;25(8):1821-9. doi: 10.1185/03007990903018360. Curr Med Res Opin. 2009. PMID: 19530977 Clinical Trial.

10

A multiple dose study of prasugrel (CS-747), a novel thienopyridine P2Y12 inhibitor, compared with clopidogrel in healthy humans.

Jakubowski JA, Matsushima N, Asai F, Naganuma H, Brandt JT, Hirota T, Freestone S, Winters KJ. Jakubowski JA, et al. Among authors: brandt jt. Br J Clin Pharmacol. 2007 Apr;63(4):421-30. doi: 10.1111/j.1365-2125.2006.02792.x. Epub 2006 Oct 31. Br J Clin Pharmacol. 2007. PMID: 17076696 Free PMC article. Clinical Trial.

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