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Thermostabilization of the neurotensin receptor NTS1.
Shibata Y, White JF, Serrano-Vega MJ, Magnani F, Aloia AL, Grisshammer R, Tate CG. Shibata Y, et al. J Mol Biol. 2009 Jul 10;390(2):262-77. doi: 10.1016/j.jmb.2009.04.068. Epub 2009 May 5. J Mol Biol. 2009. PMID: 19422831 Free PMC article.
Structure of the agonist-bound neurotensin receptor.
White JF, Noinaj N, Shibata Y, Love J, Kloss B, Xu F, Gvozdenovic-Jeremic J, Shah P, Shiloach J, Tate CG, Grisshammer R. White JF, et al. Among authors: shibata y. Nature. 2012 Oct 25;490(7421):508-13. doi: 10.1038/nature11558. Epub 2012 Oct 10. Nature. 2012. PMID: 23051748 Free PMC article.
Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Chan DTY, Jenkinson L, Haynes SW, Austin M, Diamandakis A, Burschowsky D, Seewooruthun C, Addyman A, Fiedler S, Ryman S, Whitehouse J, Slater LH, Gowans E, Shibata Y, Barnard M, Wilkinson RW, Vaughan TJ, Holt SV, Cerundolo V, Carr MD, Groves MAT. Chan DTY, et al. Among authors: shibata y. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):16949-16960. doi: 10.1073/pnas.1919565117. Epub 2020 Jul 2. Proc Natl Acad Sci U S A. 2020. PMID: 32616569 Free PMC article.
Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Austin M, Burschowsky D, Chan DTY, Jenkinson L, Haynes S, Diamandakis A, Seewooruthun C, Addyman A, Fiedler S, Ryman S, Whitehouse J, Slater LH, Hadjinicolaou AV, Gileadi U, Gowans E, Shibata Y, Barnard M, Kaserer T, Sharma P, Luheshi NM, Wilkinson RW, Vaughan TJ, Holt SV, Cerundolo V, Carr MD, Groves MAT. Austin M, et al. Among authors: shibata y. MAbs. 2020 Jan-Dec;12(1):1801230. doi: 10.1080/19420862.2020.1801230. MAbs. 2020. PMID: 32880207 Free PMC article.
Antibodies binding the head domain of P2X4 inhibit channel function and reverse neuropathic pain.
Williams WA, Linley JE, Jones CA, Shibata Y, Snijder A, Button J, Hatcher JP, Huang L, Taddese B, Thornton P, Schofield DJ, Thom G, Popovic B, Dosanjh B, Wilkinson T, Hughes J, Dobson CL, Groves MA, Webster CI, Billinton A, Vaughan TJ, Chessell I. Williams WA, et al. Among authors: shibata y. Pain. 2019 Sep;160(9):1989-2003. doi: 10.1097/j.pain.0000000000001587. Pain. 2019. PMID: 31045747
2,779 results