Tsai SC - Search Results

1

ACCase 6 is the essential acetyl-CoA carboxylase involved in fatty acid and mycolic acid biosynthesis in mycobacteria.

Kurth DG, Gago GM, de la Iglesia A, Bazet Lyonnet B, Lin TW, Morbidoni HR, Tsai SC, Gramajo H. Kurth DG, et al. Among authors: tsai sc. Microbiology (Reading). 2009 Aug;155(Pt 8):2664-2675. doi: 10.1099/mic.0.027714-0. Epub 2009 May 7. Microbiology (Reading). 2009. PMID: 19423629 Free PMC article.

2

Biochemical and structural characterization of an essential acyl coenzyme A carboxylase from Mycobacterium tuberculosis.

Gago G, Kurth D, Diacovich L, Tsai SC, Gramajo H. Gago G, et al. Among authors: tsai sc. J Bacteriol. 2006 Jan;188(2):477-86. doi: 10.1128/JB.188.2.477-486.2006. J Bacteriol. 2006. PMID: 16385038 Free PMC article.

3

Structure-based inhibitor design of AccD5, an essential acyl-CoA carboxylase carboxyltransferase domain of Mycobacterium tuberculosis.

Lin TW, Melgar MM, Kurth D, Swamidass SJ, Purdon J, Tseng T, Gago G, Baldi P, Gramajo H, Tsai SC. Lin TW, et al. Among authors: tsai sc. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3072-7. doi: 10.1073/pnas.0510580103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492739 Free PMC article.

4

Fatty acid biosynthesis in actinomycetes.

Gago G, Diacovich L, Arabolaza A, Tsai SC, Gramajo H. Gago G, et al. Among authors: tsai sc. FEMS Microbiol Rev. 2011 May;35(3):475-97. doi: 10.1111/j.1574-6976.2010.00259.x. Epub 2011 Jan 19. FEMS Microbiol Rev. 2011. PMID: 21204864 Free PMC article. Review.

5

Crystal structure of the beta-subunit of acyl-CoA carboxylase: structure-based engineering of substrate specificity.

Diacovich L, Mitchell DL, Pham H, Gago G, Melgar MM, Khosla C, Gramajo H, Tsai SC. Diacovich L, et al. Among authors: tsai sc. Biochemistry. 2004 Nov 9;43(44):14027-36. doi: 10.1021/bi049065v. Biochemistry. 2004. PMID: 15518551

6

Crystal structures and mutational analyses of acyl-CoA carboxylase beta subunit of Streptomyces coelicolor.

Arabolaza A, Shillito ME, Lin TW, Diacovich L, Melgar M, Pham H, Amick D, Gramajo H, Tsai SC. Arabolaza A, et al. Among authors: tsai sc. Biochemistry. 2010 Aug 31;49(34):7367-76. doi: 10.1021/bi1005305. Biochemistry. 2010. PMID: 20690600 Free PMC article.

7

Influence relevance voting: an accurate and interpretable virtual high throughput screening method.

Swamidass SJ, Azencott CA, Lin TW, Gramajo H, Tsai SC, Baldi P. Swamidass SJ, et al. Among authors: tsai sc. J Chem Inf Model. 2009 Apr;49(4):756-66. doi: 10.1021/ci8004379. J Chem Inf Model. 2009. PMID: 19391629 Free PMC article.

8

Inhibition kinetics and emodin cocrystal structure of a type II polyketide ketoreductase.

Korman TP, Tan YH, Wong J, Luo R, Tsai SC. Korman TP, et al. Among authors: tsai sc. Biochemistry. 2008 Feb 19;47(7):1837-47. doi: 10.1021/bi7016427. Epub 2008 Jan 19. Biochemistry. 2008. PMID: 18205400 Free PMC article.

9

A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units.

Ray L, Valentic TR, Miyazawa T, Withall DM, Song L, Milligan JC, Osada H, Takahashi S, Tsai SC, Challis GL. Ray L, et al. Among authors: tsai sc. Nat Commun. 2016 Dec 21;7:13609. doi: 10.1038/ncomms13609. Nat Commun. 2016. PMID: 28000660 Free PMC article.

10

Trapping the dynamic acyl carrier protein in fatty acid biosynthesis.

Nguyen C, Haushalter RW, Lee DJ, Markwick PR, Bruegger J, Caldara-Festin G, Finzel K, Jackson DR, Ishikawa F, O'Dowd B, McCammon JA, Opella SJ, Tsai SC, Burkart MD. Nguyen C, et al. Among authors: tsai sc. Nature. 2014 Jan 16;505(7483):427-31. doi: 10.1038/nature12810. Epub 2013 Dec 22. Nature. 2014. PMID: 24362570 Free PMC article.

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