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Page 1
Specific targeting of peripheral serotonin 5-HT(3) receptors. Synthesis, biological investigation, and structure-activity relationships.
Morelli E, Gemma S, Budriesi R, Campiani G, Novellino E, Fattorusso C, Catalanotti B, Coccone SS, Ros S, Borrelli G, Persico M, Fiorini I, Nacci V, Ioan P, Chiarini A, Hamon M, Cagnotto A, Mennini T, Fracasso C, Colovic M, Caccia S, Butini S. Morelli E, et al. Among authors: borrelli g. J Med Chem. 2009 Jun 11;52(11):3548-62. doi: 10.1021/jm900018b. J Med Chem. 2009. PMID: 19425598
Specific targeting of highly conserved residues in the HIV-1 reverse transcriptase primer grip region. 2. Stereoselective interaction to overcome the effects of drug resistant mutations.
Butini S, Brindisi M, Cosconati S, Marinelli L, Borrelli G, Coccone SS, Ramunno A, Campiani G, Novellino E, Zanoli S, Samuele A, Giorgi G, Bergamini A, Di Mattia M, Lalli S, Galletti B, Gemma S, Maga G. Butini S, et al. Among authors: borrelli g. J Med Chem. 2009 Feb 26;52(4):1224-8. doi: 10.1021/jm801395v. J Med Chem. 2009. PMID: 19170521
Novel, potent, and selective quinoxaline-based 5-HT(3) receptor ligands. 1. Further structure-activity relationships and pharmacological characterization.
Butini S, Budriesi R, Hamon M, Morelli E, Gemma S, Brindisi M, Borrelli G, Novellino E, Fiorini I, Ioan P, Chiarini A, Cagnotto A, Mennini T, Fracasso C, Caccia S, Campiani G. Butini S, et al. Among authors: borrelli g. J Med Chem. 2009 Nov 12;52(21):6946-50. doi: 10.1021/jm901126m. J Med Chem. 2009. PMID: 19831400
Discovery of bishomo(hetero)arylpiperazines as novel multifunctional ligands targeting dopamine D(3) and serotonin 5-HT(1A) and 5-HT(2A) receptors.
Butini S, Campiani G, Franceschini S, Trotta F, Kumar V, Guarino E, Borrelli G, Fiorini I, Novellino E, Fattorusso C, Persico M, Orteca N, Sandager-Nielsen K, Jacobsen TA, Madsen K, Scheel-Kruger J, Gemma S. Butini S, et al. Among authors: borrelli g. J Med Chem. 2010 Jun 24;53(12):4803-7. doi: 10.1021/jm100294b. J Med Chem. 2010. PMID: 20481570
Non-nucleoside inhibitors of human adenosine kinase: synthesis, molecular modeling, and biological studies.
Butini S, Gemma S, Brindisi M, Borrelli G, Lossani A, Ponte AM, Torti A, Maga G, Marinelli L, La Pietra V, Fiorini I, Lamponi S, Campiani G, Zisterer DM, Nathwani SM, Sartini S, La Motta C, Da Settimo F, Novellino E, Focher F. Butini S, et al. Among authors: borrelli g. J Med Chem. 2011 Mar 10;54(5):1401-20. doi: 10.1021/jm101438u. Epub 2011 Feb 14. J Med Chem. 2011. PMID: 21319802
Discovery of potent inhibitors of human and mouse fatty acid amide hydrolases.
Butini S, Brindisi M, Gemma S, Minetti P, Cabri W, Gallo G, Vincenti S, Talamonti E, Borsini F, Caprioli A, Stasi MA, Di Serio S, Ros S, Borrelli G, Maramai S, Fezza F, Campiani G, Maccarrone M. Butini S, et al. Among authors: borrelli g. J Med Chem. 2012 Aug 9;55(15):6898-915. doi: 10.1021/jm300689c. Epub 2012 Jul 26. J Med Chem. 2012. PMID: 22779702
Enantioselective binding of second generation pyrrolobenzoxazepinones to the catalytic ternary complex of HIV-1 RT wild-type and L100I and K103N drug resistant mutants.
Butini S, Gemma S, Brindisi M, Borrelli G, Fiorini I, Samuele A, Karytinos A, Facchini M, Lossani A, Zanoli S, Campiani G, Novellino E, Focher F, Maga G. Butini S, et al. Among authors: borrelli g. Bioorg Med Chem Lett. 2011 Jul 1;21(13):3935-8. doi: 10.1016/j.bmcl.2011.05.020. Epub 2011 May 14. Bioorg Med Chem Lett. 2011. PMID: 21636271
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain.
Brindisi M, Borrelli G, Brogi S, Grillo A, Maramai S, Paolino M, Benedusi M, Pecorelli A, Valacchi G, Di Cesare Mannelli L, Ghelardini C, Allarà M, Ligresti A, Minetti P, Campiani G, di Marzo V, Butini S, Gemma S. Brindisi M, et al. Among authors: borrelli g. ChemMedChem. 2018 Oct 8;13(19):2090-2103. doi: 10.1002/cmdc.201800397. Epub 2018 Aug 30. ChemMedChem. 2018. PMID: 30085402
Pancreatic Stone Protein in the Diagnosis of Sepsis in Children Admitted to High-Dependency Care: A Single-Center Prospective Cohort Study.
Bottari G, Paionni E, Fegatelli DA, Murciano M, Rosati F, Ferrigno F, Pisani M, Cristaldi S, Musolino A, Borrelli G, Bochicchio C, Romani L, De Luca M, Agosta M, Lancella L, Villani A, Vestri A, Atti MCD, Perno CF, Porzio O, Raponi M, Cecchetti C. Bottari G, et al. Among authors: borrelli g. Pediatr Crit Care Med. 2024 Oct 1;25(10):937-946. doi: 10.1097/PCC.0000000000003565. Epub 2024 Jul 18. Pediatr Crit Care Med. 2024. PMID: 39023339
112 results