High KA - Search Results

1

Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors.

Pien GC, Basner-Tschakarjan E, Hui DJ, Mentlik AN, Finn JD, Hasbrouck NC, Zhou S, Murphy SL, Maus MV, Mingozzi F, Orange JS, High KA. Pien GC, et al. Among authors: high ka. J Clin Invest. 2009 Jun;119(6):1688-95. doi: 10.1172/JCI36891. Epub 2009 May 11. J Clin Invest. 2009. PMID: 19436115 Free PMC article.

2

Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer.

Mingozzi F, Liu YL, Dobrzynski E, Kaufhold A, Liu JH, Wang Y, Arruda VR, High KA, Herzog RW. Mingozzi F, et al. Among authors: high ka. J Clin Invest. 2003 May;111(9):1347-56. doi: 10.1172/JCI16887. J Clin Invest. 2003. PMID: 12727926 Free PMC article.

3

CD8(+) T-cell responses to adeno-associated virus capsid in humans.

Mingozzi F, Maus MV, Hui DJ, Sabatino DE, Murphy SL, Rasko JE, Ragni MV, Manno CS, Sommer J, Jiang H, Pierce GF, Ertl HC, High KA. Mingozzi F, et al. Among authors: high ka. Nat Med. 2007 Apr;13(4):419-22. doi: 10.1038/nm1549. Epub 2007 Mar 18. Nat Med. 2007. PMID: 17369837

4

Prolonged susceptibility to antibody-mediated neutralization for adeno-associated vectors targeted to the liver.

Murphy SL, Li H, Zhou S, Schlachterman A, High KA. Murphy SL, et al. Among authors: high ka. Mol Ther. 2008 Jan;16(1):138-45. doi: 10.1038/sj.mt.6300334. Epub 2007 Oct 23. Mol Ther. 2008. PMID: 17955024 Free article.

5

Immune responses to AAV in clinical trials.

Mingozzi F, High KA. Mingozzi F, et al. Among authors: high ka. Curr Gene Ther. 2007 Oct;7(5):316-24. doi: 10.2174/156652307782151425. Curr Gene Ther. 2007. PMID: 17979678 Review.

6

Diverse IgG subclass responses to adeno-associated virus infection and vector administration.

Murphy SL, Li H, Mingozzi F, Sabatino DE, Hui DJ, Edmonson SA, High KA. Murphy SL, et al. Among authors: high ka. J Med Virol. 2009 Jan;81(1):65-74. doi: 10.1002/jmv.21360. J Med Virol. 2009. PMID: 19031458 Free PMC article.

7

Proteasome inhibitors decrease AAV2 capsid derived peptide epitope presentation on MHC class I following transduction.

Finn JD, Hui D, Downey HD, Dunn D, Pien GC, Mingozzi F, Zhou S, High KA. Finn JD, et al. Among authors: high ka. Mol Ther. 2010 Jan;18(1):135-42. doi: 10.1038/mt.2009.257. Epub 2009 Nov 10. Mol Ther. 2010. PMID: 19904235 Free PMC article.

8

Immune responses to AAV in clinical trials.

Mingozzi F, High KA. Mingozzi F, et al. Among authors: high ka. Curr Gene Ther. 2011 Aug;11(4):321-30. doi: 10.2174/156652311796150354. Curr Gene Ther. 2011. PMID: 21557723 Review.

9

Immune responses to AAV vectors: overcoming barriers to successful gene therapy.

Mingozzi F, High KA. Mingozzi F, et al. Among authors: high ka. Blood. 2013 Jul 4;122(1):23-36. doi: 10.1182/blood-2013-01-306647. Epub 2013 Apr 17. Blood. 2013. PMID: 23596044 Free PMC article. Review.

10

Improved hepatic gene transfer by using an adeno-associated virus serotype 5 vector.

Mingozzi F, Schüttrumpf J, Arruda VR, Liu Y, Liu YL, High KA, Xiao W, Herzog RW. Mingozzi F, et al. Among authors: high ka. J Virol. 2002 Oct;76(20):10497-502. doi: 10.1128/jvi.76.20.10497-10502.2002. J Virol. 2002. PMID: 12239326 Free PMC article.

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