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Non-nucleoside inhibitors of HCV polymerase NS5B. Part 2: Synthesis and structure-activity relationships of benzothiazine-substituted quinolinediones.
de Vicente J, Hendricks RT, Smith DB, Fell JB, Fischer J, Spencer SR, Stengel PJ, Mohr P, Robinson JE, Blake JF, Hilgenkamp RK, Yee C, Adjabeng G, Elworthy TR, Tracy J, Chin E, Li J, Wang B, Bamberg JT, Stephenson R, Oshiro C, Harris SF, Ghate M, Leveque V, Najera I, Le Pogam S, Rajyaguru S, Ao-Ieong G, Alexandrova L, Larrabee S, Brandl M, Briggs A, Sukhtankar S, Farrell R, Xu B. de Vicente J, et al. Among authors: oshiro c. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3642-6. doi: 10.1016/j.bmcl.2009.05.004. Epub 2009 May 7. Bioorg Med Chem Lett. 2009. PMID: 19457662
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 3: synthesis and optimization studies of benzothiazine-substituted tetramic acids.
de Vicente J, Hendricks RT, Smith DB, Fell JB, Fischer J, Spencer SR, Stengel PJ, Mohr P, Robinson JE, Blake JF, Hilgenkamp RK, Yee C, Zhao J, Elworthy TR, Tracy J, Chin E, Li J, Lui A, Wang B, Oshiro C, Harris SF, Ghate M, Leveque VJ, Najera I, Le Pogam S, Rajyaguru S, Ao-Ieong G, Alexandrova L, Fitch B, Brandl M, Masjedizadeh M, Wu SY, de Keczer S, Voronin T. de Vicente J, et al. Among authors: oshiro c. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5648-51. doi: 10.1016/j.bmcl.2009.08.023. Epub 2009 Aug 8. Bioorg Med Chem Lett. 2009. PMID: 19700319
Selection and characterization of replicon variants dually resistant to thumb- and palm-binding nonnucleoside polymerase inhibitors of the hepatitis C virus.
Le Pogam S, Kang H, Harris SF, Leveque V, Giannetti AM, Ali S, Jiang WR, Rajyaguru S, Tavares G, Oshiro C, Hendricks T, Klumpp K, Symons J, Browner MF, Cammack N, Nájera I. Le Pogam S, et al. Among authors: oshiro c. J Virol. 2006 Jun;80(12):6146-54. doi: 10.1128/JVI.02628-05. J Virol. 2006. PMID: 16731953 Free PMC article.
Distance geometry.
Kuntz ID, Thomason JF, Oshiro CM. Kuntz ID, et al. Among authors: oshiro cm. Methods Enzymol. 1989;177:159-204. doi: 10.1016/0076-6879(89)77011-7. Methods Enzymol. 1989. PMID: 2607979 No abstract available.
Molecular docking to ensembles of protein structures.
Knegtel RM, Kuntz ID, Oshiro CM. Knegtel RM, et al. Among authors: oshiro cm. J Mol Biol. 1997 Feb 21;266(2):424-40. doi: 10.1006/jmbi.1996.0776. J Mol Biol. 1997. PMID: 9047373
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