Zhang C - Search Results

1

Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells.

Burkard ME, Maciejowski J, Rodriguez-Bravo V, Repka M, Lowery DM, Clauser KR, Zhang C, Shokat KM, Carr SA, Yaffe MB, Jallepalli PV. Burkard ME, et al. Among authors: zhang c. PLoS Biol. 2009 May 5;7(5):e1000111. doi: 10.1371/journal.pbio.1000111. Epub 2009 May 26. PLoS Biol. 2009. PMID: 19468302 Free PMC article.

2

Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling.

Maciejowski J, George KA, Terret ME, Zhang C, Shokat KM, Jallepalli PV. Maciejowski J, et al. Among authors: zhang c. J Cell Biol. 2010 Jul 12;190(1):89-100. doi: 10.1083/jcb.201001050. J Cell Biol. 2010. PMID: 20624902 Free PMC article.

3

Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells.

Burkard ME, Randall CL, Larochelle S, Zhang C, Shokat KM, Fisher RP, Jallepalli PV. Burkard ME, et al. Among authors: zhang c. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4383-8. doi: 10.1073/pnas.0701140104. Epub 2007 Mar 6. Proc Natl Acad Sci U S A. 2007. PMID: 17360533 Free PMC article.

4

Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.

Larochelle S, Merrick KA, Terret ME, Wohlbold L, Barboza NM, Zhang C, Shokat KM, Jallepalli PV, Fisher RP. Larochelle S, et al. Among authors: zhang c. Mol Cell. 2007 Mar 23;25(6):839-50. doi: 10.1016/j.molcel.2007.02.003. Mol Cell. 2007. PMID: 17386261 Free PMC article.

5

A coupled chemical-genetic and bioinformatic approach to Polo-like kinase pathway exploration.

Snead JL, Sullivan M, Lowery DM, Cohen MS, Zhang C, Randle DH, Taunton J, Yaffe MB, Morgan DO, Shokat KM. Snead JL, et al. Among authors: zhang c. Chem Biol. 2007 Nov;14(11):1261-72. doi: 10.1016/j.chembiol.2007.09.011. Chem Biol. 2007. PMID: 18022565 Free PMC article.

6

Distinct activation pathways confer cyclin-binding specificity on Cdk1 and Cdk2 in human cells.

Merrick KA, Larochelle S, Zhang C, Allen JJ, Shokat KM, Fisher RP. Merrick KA, et al. Among authors: zhang c. Mol Cell. 2008 Dec 5;32(5):662-72. doi: 10.1016/j.molcel.2008.10.022. Mol Cell. 2008. PMID: 19061641 Free PMC article.

7

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF.

Poulikakos PI, Zhang C, Bollag G, Shokat KM, Rosen N. Poulikakos PI, et al. Among authors: zhang c. Nature. 2010 Mar 18;464(7287):427-30. doi: 10.1038/nature08902. Nature. 2010. PMID: 20179705 Free PMC article.

8

Chemical genetic inhibition of Mps1 in stable human cell lines reveals novel aspects of Mps1 function in mitosis.

Sliedrecht T, Zhang C, Shokat KM, Kops GJ. Sliedrecht T, et al. Among authors: zhang c. PLoS One. 2010 Apr 22;5(4):e10251. doi: 10.1371/journal.pone.0010251. PLoS One. 2010. PMID: 20422024 Free PMC article.

9

Sole BCR-ABL inhibition is insufficient to eliminate all myeloproliferative disorder cell populations.

Wong S, McLaughlin J, Cheng D, Zhang C, Shokat KM, Witte ON. Wong S, et al. Among authors: zhang c. Proc Natl Acad Sci U S A. 2004 Dec 14;101(50):17456-61. doi: 10.1073/pnas.0407061101. Epub 2004 Oct 25. Proc Natl Acad Sci U S A. 2004. PMID: 15505216 Free PMC article.

10

Structural bioinformatics-based design of selective, irreversible kinase inhibitors.

Cohen MS, Zhang C, Shokat KM, Taunton J. Cohen MS, et al. Among authors: zhang c. Science. 2005 May 27;308(5726):1318-21. doi: 10.1126/science1108367. Science. 2005. PMID: 15919995 Free PMC article.

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