Biechele TL - Search Results

1

Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling.

James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT. James RG, et al. Among authors: biechele tl. Sci Signal. 2009 May 26;2(72):ra25. doi: 10.1126/scisignal.2000230. Sci Signal. 2009. PMID: 19471023 Free PMC article.

2

Bili inhibits Wnt/beta-catenin signaling by regulating the recruitment of axin to LRP6.

Kategaya LS, Changkakoty B, Biechele T, Conrad WH, Kaykas A, Dasgupta R, Moon RT. Kategaya LS, et al. PLoS One. 2009 Jul 2;4(7):e6129. doi: 10.1371/journal.pone.0006129. PLoS One. 2009. PMID: 19572019 Free PMC article.

3

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation.

Angers S, Thorpe CJ, Biechele TL, Goldenberg SJ, Zheng N, MacCoss MJ, Moon RT. Angers S, et al. Among authors: biechele tl. Nat Cell Biol. 2006 Apr;8(4):348-57. doi: 10.1038/ncb1381. Epub 2006 Mar 19. Nat Cell Biol. 2006. PMID: 16547521

4

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.

Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT. Major MB, et al. Among authors: biechele tl. Science. 2007 May 18;316(5827):1043-6. doi: 10.1126/science/1141515. Science. 2007. PMID: 17510365

5

Assaying beta-catenin/TCF transcription with beta-catenin/TCF transcription-based reporter constructs.

Biechele TL, Moon RT. Biechele TL, et al. Methods Mol Biol. 2008;468:99-110. doi: 10.1007/978-1-59745-249-6_8. Methods Mol Biol. 2008. PMID: 19099249

6

Integrative analysis of genome-wide RNA interference screens.

Berndt JD, Biechele TL, Moon RT, Major MB. Berndt JD, et al. Among authors: biechele tl. Sci Signal. 2009 May 12;2(70):pt4. doi: 10.1126/scisignal.270pt4. Sci Signal. 2009. PMID: 19436058

7

Transcription-based reporters of Wnt/beta-catenin signaling.

Biechele TL, Adams AM, Moon RT. Biechele TL, et al. Cold Spring Harb Protoc. 2009 Jun;2009(6):pdb.prot5223. doi: 10.1101/pdb.prot5223. Cold Spring Harb Protoc. 2009. PMID: 20147181 No abstract available.

8

Chemical-genetic screen identifies riluzole as an enhancer of Wnt/β-catenin signaling in melanoma.

Biechele TL, Camp ND, Fass DM, Kulikauskas RM, Robin NC, White BD, Taraska CM, Moore EC, Muster J, Karmacharya R, Haggarty SJ, Chien AJ, Moon RT. Biechele TL, et al. Chem Biol. 2010 Nov 24;17(11):1177-82. doi: 10.1016/j.chembiol.2010.08.012. Chem Biol. 2010. PMID: 21095567 Free PMC article.

9

Wnt/β-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma.

Biechele TL, Kulikauskas RM, Toroni RA, Lucero OM, Swift RD, James RG, Robin NC, Dawson DW, Moon RT, Chien AJ. Biechele TL, et al. Sci Signal. 2012 Jan 10;5(206):ra3. doi: 10.1126/scisignal.2002274. Sci Signal. 2012. PMID: 22234612 Free PMC article.

10

Regulating the response to targeted MEK inhibition in melanoma: enhancing apoptosis in NRAS- and BRAF-mutant melanoma cells with Wnt/β-catenin activation.

Conrad WH, Swift RD, Biechele TL, Kulikauskas RM, Moon RT, Chien AJ. Conrad WH, et al. Among authors: biechele tl. Cell Cycle. 2012 Oct 15;11(20):3724-30. doi: 10.4161/cc.21645. Epub 2012 Aug 16. Cell Cycle. 2012. PMID: 22895053 Free PMC article.

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