Wang D - Search Results

1

Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.

Wang D, Bushnell DA, Huang X, Westover KD, Levitt M, Kornberg RD. Wang D, et al. Science. 2009 May 29;324(5931):1203-6. doi: 10.1126/science.1168729. Science. 2009. PMID: 19478184 Free PMC article.

2

Ubiquitin ligase activity of TFIIH and the transcriptional response to DNA damage.

Takagi Y, Masuda CA, Chang WH, Komori H, Wang D, Hunter T, Joazeiro CA, Kornberg RD. Takagi Y, et al. Among authors: wang d. Mol Cell. 2005 Apr 15;18(2):237-43. doi: 10.1016/j.molcel.2005.03.007. Mol Cell. 2005. PMID: 15837426 Free article.

3

Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis.

Wang D, Bushnell DA, Westover KD, Kaplan CD, Kornberg RD. Wang D, et al. Cell. 2006 Dec 1;127(5):941-54. doi: 10.1016/j.cell.2006.11.023. Cell. 2006. PMID: 17129781 Free PMC article.

4

Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism.

Liu X, Bushnell DA, Wang D, Calero G, Kornberg RD. Liu X, et al. Among authors: wang d. Science. 2010 Jan 8;327(5962):206-9. doi: 10.1126/science.1182015. Epub 2009 Nov 12. Science. 2010. PMID: 19965383 Free PMC article.

5

X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.

Wang D, Zhu G, Huang X, Lippard SJ. Wang D, et al. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9584-9. doi: 10.1073/pnas.1002565107. Epub 2010 May 6. Proc Natl Acad Sci U S A. 2010. PMID: 20448203 Free PMC article.

6

RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription.

Huang X, Wang D, Weiss DR, Bushnell DA, Kornberg RD, Levitt M. Huang X, et al. Among authors: wang d. Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15745-50. doi: 10.1073/pnas.1009898107. Epub 2010 Aug 23. Proc Natl Acad Sci U S A. 2010. PMID: 20798057 Free PMC article.

7

Dynamics of pyrophosphate ion release and its coupled trigger loop motion from closed to open state in RNA polymerase II.

Da LT, Wang D, Huang X. Da LT, et al. Among authors: wang d. J Am Chem Soc. 2012 Feb 1;134(4):2399-406. doi: 10.1021/ja210656k. Epub 2012 Jan 24. J Am Chem Soc. 2012. PMID: 22206270 Free PMC article.

8

A two-state model for the dynamics of the pyrophosphate ion release in bacterial RNA polymerase.

Da LT, Pardo Avila F, Wang D, Huang X. Da LT, et al. Among authors: wang d. PLoS Comput Biol. 2013 Apr;9(4):e1003020. doi: 10.1371/journal.pcbi.1003020. Epub 2013 Apr 4. PLoS Comput Biol. 2013. PMID: 23592966 Free PMC article.

9

Dissecting the chemical interactions and substrate structural signatures governing RNA polymerase II trigger loop closure by synthetic nucleic acid analogues.

Xu L, Butler KV, Chong J, Wengel J, Kool ET, Wang D. Xu L, et al. Among authors: wang d. Nucleic Acids Res. 2014 May;42(9):5863-70. doi: 10.1093/nar/gku238. Epub 2014 Apr 1. Nucleic Acids Res. 2014. PMID: 24692664 Free PMC article.

10

Millisecond dynamics of RNA polymerase II translocation at atomic resolution.

Silva DA, Weiss DR, Pardo Avila F, Da LT, Levitt M, Wang D, Huang X. Silva DA, et al. Among authors: wang d. Proc Natl Acad Sci U S A. 2014 May 27;111(21):7665-70. doi: 10.1073/pnas.1315751111. Epub 2014 Apr 21. Proc Natl Acad Sci U S A. 2014. PMID: 24753580 Free PMC article.

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