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Page 1
PDGF receptors as cancer drug targets.
Pietras K, Sjöblom T, Rubin K, Heldin CH, Ostman A. Pietras K, et al. Among authors: heldin ch. Cancer Cell. 2003 May;3(5):439-43. doi: 10.1016/s1535-6108(03)00089-8. Cancer Cell. 2003. PMID: 12781361 Free article. Review. No abstract available.
Preferential oxidation of the second phosphatase domain of receptor-like PTP-alpha revealed by an antibody against oxidized protein tyrosine phosphatases.
Persson C, Sjöblom T, Groen A, Kappert K, Engström U, Hellman U, Heldin CH, den Hertog J, Ostman A. Persson C, et al. Among authors: heldin ch. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1886-91. doi: 10.1073/pnas.0304403101. Epub 2004 Feb 4. Proc Natl Acad Sci U S A. 2004. PMID: 14762163 Free PMC article.
Oral imatinib mesylate (STI571/gleevec) improves the efficacy of local intravascular vascular endothelial growth factor-C gene transfer in reducing neointimal growth in hypercholesterolemic rabbits.
Leppänen O, Rutanen J, Hiltunen MO, Rissanen TT, Turunen MP, Sjöblom T, Brüggen J, Bäckström G, Carlsson M, Buchdunger E, Bergqvist D, Alitalo K, Heldin CH, Ostman A, Ylä-Herttuala S. Leppänen O, et al. Among authors: heldin ch. Circulation. 2004 Mar 9;109(9):1140-6. doi: 10.1161/01.CIR.0000117234.08626.7C. Epub 2004 Feb 9. Circulation. 2004. PMID: 14769706
Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase.
Persson C, Sävenhed C, Bourdeau A, Tremblay ML, Markova B, Böhmer FD, Haj FG, Neel BG, Elson A, Heldin CH, Rönnstrand L, Ostman A, Hellberg C. Persson C, et al. Among authors: heldin ch. Mol Cell Biol. 2004 Mar;24(5):2190-201. doi: 10.1128/MCB.24.5.2190-2201.2004. Mol Cell Biol. 2004. PMID: 14966296 Free PMC article.
Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate.
Furuhashi M, Sjöblom T, Abramsson A, Ellingsen J, Micke P, Li H, Bergsten-Folestad E, Eriksson U, Heuchel R, Betsholtz C, Heldin CH, Ostman A. Furuhashi M, et al. Among authors: heldin ch. Cancer Res. 2004 Apr 15;64(8):2725-33. doi: 10.1158/0008-5472.can-03-1489. Cancer Res. 2004. PMID: 15087386
585 results