Gryaznov SM - Search Results

1

The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel.

Goldblatt EM, Gentry ER, Fox MJ, Gryaznov SM, Shen C, Herbert BS. Goldblatt EM, et al. Among authors: gryaznov sm. Mol Cancer Ther. 2009 Jul;8(7):2027-35. doi: 10.1158/1535-7163.MCT-08-1188. Epub 2009 Jun 9. Mol Cancer Ther. 2009. PMID: 19509275

2

Telomerase template antagonist GRN163L disrupts telomere maintenance, tumor growth, and metastasis of breast cancer.

Hochreiter AE, Xiao H, Goldblatt EM, Gryaznov SM, Miller KD, Badve S, Sledge GW, Herbert BS. Hochreiter AE, et al. Among authors: gryaznov sm. Clin Cancer Res. 2006 May 15;12(10):3184-92. doi: 10.1158/1078-0432.CCR-05-2760. Clin Cancer Res. 2006. PMID: 16707619

3

Specific telomere dysfunction induced by GRN163L increases radiation sensitivity in breast cancer cells.

Gomez-Millan J, Goldblatt EM, Gryaznov SM, Mendonca MS, Herbert BS. Gomez-Millan J, et al. Among authors: gryaznov sm. Int J Radiat Oncol Biol Phys. 2007 Mar 1;67(3):897-905. doi: 10.1016/j.ijrobp.2006.09.038. Epub 2006 Dec 15. Int J Radiat Oncol Biol Phys. 2007. PMID: 17175117

4

Lipid-conjugated telomerase template antagonists sensitize resistant HER2-positive breast cancer cells to trastuzumab.

Goldblatt EM, Erickson PA, Gentry ER, Gryaznov SM, Herbert BS. Goldblatt EM, et al. Among authors: gryaznov sm. Breast Cancer Res Treat. 2009 Nov;118(1):21-32. doi: 10.1007/s10549-008-0201-4. Epub 2008 Oct 14. Breast Cancer Res Treat. 2009. PMID: 18853252

5

Oligonucleotide conjugate GRN163L targeting human telomerase as potential anticancer and antimetastatic agent.

Gryaznov SM, Jackson S, Dikmen G, Harley C, Herbert BS, Wright WE, Shay JW. Gryaznov SM, et al. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1577-9. doi: 10.1080/15257770701547271. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066830

6

Oligonucleotide N3'-->P5' phosphoramidates as efficient telomerase inhibitors.

Herbert BS, Pongracz K, Shay JW, Gryaznov SM. Herbert BS, et al. Among authors: gryaznov sm. Oncogene. 2002 Jan 21;21(4):638-42. doi: 10.1038/sj.onc.1205064. Oncogene. 2002. PMID: 11850790

7

Targeting critical steps of cancer metastasis and recurrence using telomerase template antagonists.

Dikmen ZG, Ozgurtas T, Gryaznov SM, Herbert BS. Dikmen ZG, et al. Among authors: gryaznov sm. Biochim Biophys Acta. 2009 Apr;1792(4):240-7. doi: 10.1016/j.bbadis.2009.01.018. Epub 2009 Feb 9. Biochim Biophys Acta. 2009. PMID: 19419695 Free article. Review.

8

Lipid modification of GRN163, an N3'-->P5' thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition.

Herbert BS, Gellert GC, Hochreiter A, Pongracz K, Wright WE, Zielinska D, Chin AC, Harley CB, Shay JW, Gryaznov SM. Herbert BS, et al. Among authors: gryaznov sm. Oncogene. 2005 Aug 4;24(33):5262-8. doi: 10.1038/sj.onc.1208760. Oncogene. 2005. PMID: 15940257

9

Telomerase inhibition improves tumor response to radiotherapy in a murine orthotopic model of human glioblastoma.

Ferrandon S, Malleval C, El Hamdani B, Battiston-Montagne P, Bolbos R, Langlois JB, Manas P, Gryaznov SM, Alphonse G, Honnorat J, Rodriguez-Lafrasse C, Poncet D. Ferrandon S, et al. Among authors: gryaznov sm. Mol Cancer. 2015 Jul 17;14:134. doi: 10.1186/s12943-015-0376-3. Mol Cancer. 2015. PMID: 26183089 Free PMC article.

10

Novel short oligonucleotide conjugates as inhibitors of human telomerase.

Pongracz K, Li S, Herbert BS, Pruzan R, Wunder E, Chin A, Piatyszek M, Shay J, Gryaznov SM. Pongracz K, et al. Among authors: gryaznov sm. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1627-9. doi: 10.1081/NCN-120023085. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565482

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