Herbert BS - Search Results

1

The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel.

Goldblatt EM, Gentry ER, Fox MJ, Gryaznov SM, Shen C, Herbert BS. Goldblatt EM, et al. Among authors: herbert bs. Mol Cancer Ther. 2009 Jul;8(7):2027-35. doi: 10.1158/1535-7163.MCT-08-1188. Epub 2009 Jun 9. Mol Cancer Ther. 2009. PMID: 19509275

2

Oligonucleotide N3'-->P5' phosphoramidates as efficient telomerase inhibitors.

Herbert BS, Pongracz K, Shay JW, Gryaznov SM. Herbert BS, et al. Oncogene. 2002 Jan 21;21(4):638-42. doi: 10.1038/sj.onc.1205064. Oncogene. 2002. PMID: 11850790

3

Novel short oligonucleotide conjugates as inhibitors of human telomerase.

Pongracz K, Li S, Herbert BS, Pruzan R, Wunder E, Chin A, Piatyszek M, Shay J, Gryaznov SM. Pongracz K, et al. Among authors: herbert bs. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1627-9. doi: 10.1081/NCN-120023085. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565482

4

Lipid modification of GRN163, an N3'-->P5' thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition.

Herbert BS, Gellert GC, Hochreiter A, Pongracz K, Wright WE, Zielinska D, Chin AC, Harley CB, Shay JW, Gryaznov SM. Herbert BS, et al. Oncogene. 2005 Aug 4;24(33):5262-8. doi: 10.1038/sj.onc.1208760. Oncogene. 2005. PMID: 15940257

5

Telomerase template antagonist GRN163L disrupts telomere maintenance, tumor growth, and metastasis of breast cancer.

Hochreiter AE, Xiao H, Goldblatt EM, Gryaznov SM, Miller KD, Badve S, Sledge GW, Herbert BS. Hochreiter AE, et al. Among authors: herbert bs. Clin Cancer Res. 2006 May 15;12(10):3184-92. doi: 10.1158/1078-0432.CCR-05-2760. Clin Cancer Res. 2006. PMID: 16707619

6

Specific telomere dysfunction induced by GRN163L increases radiation sensitivity in breast cancer cells.

Gomez-Millan J, Goldblatt EM, Gryaznov SM, Mendonca MS, Herbert BS. Gomez-Millan J, et al. Among authors: herbert bs. Int J Radiat Oncol Biol Phys. 2007 Mar 1;67(3):897-905. doi: 10.1016/j.ijrobp.2006.09.038. Epub 2006 Dec 15. Int J Radiat Oncol Biol Phys. 2007. PMID: 17175117

7

Oligonucleotide conjugate GRN163L targeting human telomerase as potential anticancer and antimetastatic agent.

Gryaznov SM, Jackson S, Dikmen G, Harley C, Herbert BS, Wright WE, Shay JW. Gryaznov SM, et al. Among authors: herbert bs. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1577-9. doi: 10.1080/15257770701547271. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066830

8

Lipid-conjugated telomerase template antagonists sensitize resistant HER2-positive breast cancer cells to trastuzumab.

Goldblatt EM, Erickson PA, Gentry ER, Gryaznov SM, Herbert BS. Goldblatt EM, et al. Among authors: herbert bs. Breast Cancer Res Treat. 2009 Nov;118(1):21-32. doi: 10.1007/s10549-008-0201-4. Epub 2008 Oct 14. Breast Cancer Res Treat. 2009. PMID: 18853252

9

Targeting critical steps of cancer metastasis and recurrence using telomerase template antagonists.

Dikmen ZG, Ozgurtas T, Gryaznov SM, Herbert BS. Dikmen ZG, et al. Among authors: herbert bs. Biochim Biophys Acta. 2009 Apr;1792(4):240-7. doi: 10.1016/j.bbadis.2009.01.018. Epub 2009 Feb 9. Biochim Biophys Acta. 2009. PMID: 19419695 Free article. Review.

10

Medical genetics and epigenetics of telomerase.

Koziel JE, Fox MJ, Steding CE, Sprouse AA, Herbert BS. Koziel JE, et al. Among authors: herbert bs. J Cell Mol Med. 2011 Mar;15(3):457-67. doi: 10.1111/j.1582-4934.2011.01276.x. J Cell Mol Med. 2011. PMID: 21323862 Free PMC article. Review.

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