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2-Phenylacetylenesulfonamide (PAS) induces p53-independent apoptotic killing of B-chronic lymphocytic leukemia (CLL) cells.
Steele AJ, Prentice AG, Hoffbrand AV, Yogashangary BC, Hart SM, Lowdell MW, Samuel ER, North JM, Nacheva EP, Chanalaris A, Kottaridis P, Cwynarski K, Wickremasinghe RG. Steele AJ, et al. Among authors: hart sm. Blood. 2009 Aug 6;114(6):1217-25. doi: 10.1182/blood-2008-11-190587. Epub 2009 Jun 10. Blood. 2009. PMID: 19515722 Free article.
The JAK3-selective inhibitor PF-956980 reverses the resistance to cytotoxic agents induced by interleukin-4 treatment of chronic lymphocytic leukemia cells: potential for reversal of cytoprotection by the microenvironment.
Steele AJ, Prentice AG, Cwynarski K, Hoffbrand AV, Hart SM, Lowdell MW, Samuel ER, Wickremasinghe RG. Steele AJ, et al. Among authors: hart sm. Blood. 2010 Nov 25;116(22):4569-77. doi: 10.1182/blood-2009-09-245811. Epub 2010 Aug 17. Blood. 2010. PMID: 20716767 Free article.
p53-mediated apoptosis of CLL cells: evidence for a transcription-independent mechanism.
Steele AJ, Prentice AG, Hoffbrand AV, Yogashangary BC, Hart SM, Nacheva EP, Howard-Reeves JD, Duke VM, Kottaridis PD, Cwynarski K, Vassilev LT, Wickremasinghe RG. Steele AJ, et al. Among authors: hart sm. Blood. 2008 Nov 1;112(9):3827-34. doi: 10.1182/blood-2008-05-156380. Epub 2008 Aug 5. Blood. 2008. PMID: 18682598 Free article.
66 results