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3,418 results

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Page 1
Discovery of a potent and orally active hedgehog pathway antagonist (IPI-926).
Tremblay MR, Lescarbeau A, Grogan MJ, Tan E, Lin G, Austad BC, Yu LC, Behnke ML, Nair SJ, Hagel M, White K, Conley J, Manna JD, Alvarez-Diez TM, Hoyt J, Woodward CN, Sydor JR, Pink M, MacDougall J, Campbell MJ, Cushing J, Ferguson J, Curtis MS, McGovern K, Read MA, Palombella VJ, Adams J, Castro AC. Tremblay MR, et al. Among authors: ferguson j. J Med Chem. 2009 Jul 23;52(14):4400-18. doi: 10.1021/jm900305z. J Med Chem. 2009. PMID: 19522463
The pre-clinical absorption, distribution, metabolism and excretion properties of IPI-926, an orally bioavailable antagonist of the hedgehog signal transduction pathway.
Smith S, Hoyt J, Whitebread N, Manna J, Peluso M, Faia K, Campbell V, Tremblay M, Nair S, Grogan M, Castro A, Campbell M, Ferguson J, Arsenault B, Nevejans J, Carter B, Lee J, Dunbar J, McGovern K, Read M, Adams J, Constan A, Loewen G, Sydor J, Palombella V, Soglia J. Smith S, et al. Among authors: ferguson j. Xenobiotica. 2013 Oct;43(10):875-85. doi: 10.3109/00498254.2013.780671. Epub 2013 Mar 25. Xenobiotica. 2013. PMID: 23527529
Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model.
McCann CK, Growdon WB, Kulkarni-Datar K, Curley MD, Friel AM, Proctor JL, Sheikh H, Deyneko I, Ferguson JA, Vathipadiekal V, Birrer MJ, Borger DR, Mohapatra G, Zukerberg LR, Foster R, Macdougall JR, Rueda BR. McCann CK, et al. Among authors: ferguson ja. PLoS One. 2011;6(11):e28077. doi: 10.1371/journal.pone.0028077. Epub 2011 Nov 29. PLoS One. 2011. PMID: 22140510 Free PMC article.
Broadly inhibitory antibodies to severe malaria virulence proteins.
Reyes RA, Raghavan SSR, Hurlburt NK, Introini V, Bol S, Kana IH, Jensen RW, Martinez-Scholze E, Gestal-Mato M, López-Gutiérrez B, Sanz S, Bancells C, Fernández-Quintero ML, Loeffler JR, Ferguson JA, Lee WH, Martin GM, Theander TG, Lusingu JPA, Minja DTR, Ssewanyana I, Feeney ME, Greenhouse B, Ward AB, Bernabeu M, Pancera M, Turner L, Bunnik EM, Lavstsen T. Reyes RA, et al. Among authors: ferguson ja. Nature. 2024 Nov 20. doi: 10.1038/s41586-024-08220-3. Online ahead of print. Nature. 2024. PMID: 39567685
A self-efficacy enhancement alcohol reduction intervention for men on-remand in prison: the APPRAISE feasibility pilot RCT.
Holloway A, Waller G, Ferguson J, Guthrie V, Smith JB, Boyd J, Mercado S, Rees J, Anthony Parker R, Stoddart A, Bray JW, Coulton S, Hunt K, Stadler G, Sondhi A, Smith P, Stenhouse R, Conaglen P, Sheikh A, Newbury-Birch D. Holloway A, et al. Among authors: ferguson j. Public Health Res (Southampt). 2024 Nov;12(11):1-186. doi: 10.3310/KNWT4781. Public Health Res (Southampt). 2024. PMID: 39545635 Clinical Trial.
Do mindfulness interventions cause harm? Findings from the Learning to Apply Mindfulness to Pain (LAMP) Pragmatic Clinical Trial.
Burgess DJ, Calvert C, Bangerter A, Branson M, Cross LJS, Evans R, Ferguson JE, Friedman JK, Hagel Campbell EM, Haley AC, Hennessy S, Kraft C, Mahaffey M, Matthias MS, Meis LA, Serpa JG, Taylor SL, Taylor BC. Burgess DJ, et al. Among authors: ferguson je. Pain Med. 2024 Nov 1;25(Supplement_1):S68-S76. doi: 10.1093/pm/pnae056. Pain Med. 2024. PMID: 39514882 Free PMC article. Clinical Trial.
3,418 results