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Detection of a secreted metalloprotease within the nuclei of liver cells.
Hunt RC, Geetha S, Allen CE, Hershko K, Fathke R, Kong PL, Plum E, Struble EB, Soejima K, Friedman S, Garfield S, Balaji S, Kimchi-Sarfaty C. Hunt RC, et al. Mol Biosyst. 2011 Jun;7(6):2012-8. doi: 10.1039/c0mb00303d. Epub 2011 Apr 11. Mol Biosyst. 2011. PMID: 21479334 Free PMC article.
Conditional deletion of CEACAM1 in hepatic stellate cells causes their activation.
Muturi HT, Ghadieh HE, Asalla S, Lester SG, Belew GD, Zaidi S, Abdolahipour R, Shrestha AP, Portuphy AO, Stankus HL, Helal RA, Verhulst S, Duarte S, Zarrinpar A, van Grunsven LA, Friedman SL, Schwabe RF, Hinds TD Jr, Kumarasamy S, Najjar SM. Muturi HT, et al. Among authors: friedman sl. Mol Metab. 2024 Oct;88:102010. doi: 10.1016/j.molmet.2024.102010. Epub 2024 Aug 19. Mol Metab. 2024. PMID: 39168268 Free PMC article.
Aramchol improves hepatic fibrosis in metabolic dysfunction-associated steatohepatitis: Results of multimodality assessment using both conventional and digital pathology.
Ratziu V, Yilmaz Y, Lazas D, Friedman SL, Lackner C, Behling C, Cummings OW, Chen L, Petitjean M, Gilgun-Sherki Y, Gorfine T, Kadosh S, Eyal E, Sanyal AJ. Ratziu V, et al. Among authors: friedman sl. Hepatology. 2024 Jun 25. doi: 10.1097/HEP.0000000000000980. Online ahead of print. Hepatology. 2024. PMID: 38916482
An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD).
Vacca M, Kamzolas I, Harder LM, Oakley F, Trautwein C, Hatting M, Ross T, Bernardo B, Oldenburger A, Hjuler ST, Ksiazek I, Lindén D, Schuppan D, Rodriguez-Cuenca S, Tonini MM, Castañeda TR, Kannt A, Rodrigues CMP, Cockell S, Govaere O, Daly AK, Allison M, Honnens de Lichtenberg K, Kim YO, Lindblom A, Oldham S, Andréasson AC, Schlerman F, Marioneaux J, Sanyal A, Afonso MB, Younes R, Amano Y, Friedman SL, Wang S, Bhattacharya D, Simon E, Paradis V, Burt A, Grypari IM, Davies S, Driessen A, Yashiro H, Pors S, Worm Andersen M, Feigh M, Yunis C, Bedossa P, Stewart M, Cater HL, Wells S, Schattenberg JM, Anstee QM; LITMUS Investigators; Tiniakos D, Perfield JW, Petsalaki E, Davidsen P, Vidal-Puig A. Vacca M, et al. Among authors: friedman sl. Nat Metab. 2024 Jun;6(6):1178-1196. doi: 10.1038/s42255-024-01043-6. Epub 2024 Jun 12. Nat Metab. 2024. PMID: 38867022 Free PMC article.
Conditional deletion of CEACAM1 causes hepatic stellate cell activation.
Muturi HT, Ghadieh HE, Asalla S, Lester SG, Verhulst S, Stankus HL, Zaidi S, Abdolahipour R, Belew GD, van Grunsven LA, Friedman SL, Schwabe RF, Hinds TD, Najjar SM. Muturi HT, et al. Among authors: friedman sl. bioRxiv [Preprint]. 2024 Apr 3:2024.04.02.586238. doi: 10.1101/2024.04.02.586238. bioRxiv. 2024. Update in: Mol Metab. 2024 Oct;88:102010. doi: 10.1016/j.molmet.2024.102010 PMID: 38617330 Free PMC article. Updated. Preprint.
525 results