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SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats.
Erion DM, Yonemitsu S, Nie Y, Nagai Y, Gillum MP, Hsiao JJ, Iwasaki T, Stark R, Weismann D, Yu XX, Murray SF, Bhanot S, Monia BP, Horvath TL, Gao Q, Samuel VT, Shulman GI. Erion DM, et al. Among authors: horvath tl. Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11288-93. doi: 10.1073/pnas.0812931106. Epub 2009 Jun 22. Proc Natl Acad Sci U S A. 2009. PMID: 19549853 Free PMC article.
Neurobiology of feeding and energy expenditure.
Gao Q, Horvath TL. Gao Q, et al. Among authors: horvath tl. Annu Rev Neurosci. 2007;30:367-98. doi: 10.1146/annurev.neuro.30.051606.094324. Annu Rev Neurosci. 2007. PMID: 17506645 Review.
Neuronal control of energy homeostasis.
Gao Q, Horvath TL. Gao Q, et al. Among authors: horvath tl. FEBS Lett. 2008 Jan 9;582(1):132-41. doi: 10.1016/j.febslet.2007.11.063. Epub 2007 Dec 3. FEBS Lett. 2008. PMID: 18061579 Free PMC article. Review.
UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals.
Andrews ZB, Liu ZW, Walllingford N, Erion DM, Borok E, Friedman JM, Tschöp MH, Shanabrough M, Cline G, Shulman GI, Coppola A, Gao XB, Horvath TL, Diano S. Andrews ZB, et al. Among authors: horvath tl. Nature. 2008 Aug 14;454(7206):846-51. doi: 10.1038/nature07181. Epub 2008 Jul 30. Nature. 2008. PMID: 18668043 Free PMC article.
STAT3 inhibition of gluconeogenesis is downregulated by SirT1.
Nie Y, Erion DM, Yuan Z, Dietrich M, Shulman GI, Horvath TL, Gao Q. Nie Y, et al. Among authors: horvath tl. Nat Cell Biol. 2009 Apr;11(4):492-500. doi: 10.1038/ncb1857. Epub 2009 Mar 22. Nat Cell Biol. 2009. PMID: 19295512 Free PMC article.
382 results