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Page 1
SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats.
Erion DM, Yonemitsu S, Nie Y, Nagai Y, Gillum MP, Hsiao JJ, Iwasaki T, Stark R, Weismann D, Yu XX, Murray SF, Bhanot S, Monia BP, Horvath TL, Gao Q, Samuel VT, Shulman GI. Erion DM, et al. Among authors: hsiao jj. Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11288-93. doi: 10.1073/pnas.0812931106. Epub 2009 Jun 22. Proc Natl Acad Sci U S A. 2009. PMID: 19549853 Free PMC article.
Knockdown of the gene encoding Drosophila tribbles homologue 3 (Trib3) improves insulin sensitivity through peroxisome proliferator-activated receptor-γ (PPAR-γ) activation in a rat model of insulin resistance.
Weismann D, Erion DM, Ignatova-Todorava I, Nagai Y, Stark R, Hsiao JJ, Flannery C, Birkenfeld AL, May T, Kahn M, Zhang D, Yu XX, Murray SF, Bhanot S, Monia BP, Cline GW, Shulman GI, Samuel VT. Weismann D, et al. Among authors: hsiao jj. Diabetologia. 2011 Apr;54(4):935-44. doi: 10.1007/s00125-010-1984-5. Epub 2010 Dec 29. Diabetologia. 2011. PMID: 21190014 Free PMC article.
Prevention of hepatic steatosis and hepatic insulin resistance by knockdown of cAMP response element-binding protein.
Erion DM, Ignatova ID, Yonemitsu S, Nagai Y, Chatterjee P, Weismann D, Hsiao JJ, Zhang D, Iwasaki T, Stark R, Flannery C, Kahn M, Carmean CM, Yu XX, Murray SF, Bhanot S, Monia BP, Cline GW, Samuel VT, Shulman GI. Erion DM, et al. Among authors: hsiao jj. Cell Metab. 2009 Dec;10(6):499-506. doi: 10.1016/j.cmet.2009.10.007. Cell Metab. 2009. PMID: 19945407 Free PMC article.
The role of the carbohydrate response element-binding protein in male fructose-fed rats.
Erion DM, Popov V, Hsiao JJ, Vatner D, Mitchell K, Yonemitsu S, Nagai Y, Kahn M, Gillum MP, Dong J, Murray SF, Manchem VP, Bhanot S, Cline GW, Shulman GI, Samuel VT. Erion DM, et al. Among authors: hsiao jj. Endocrinology. 2013 Jan;154(1):36-44. doi: 10.1210/en.2012-1725. Epub 2012 Nov 16. Endocrinology. 2013. PMID: 23161873 Free PMC article.
cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 2 (CRTC2) promotes glucagon clearance and hepatic amino acid catabolism to regulate glucose homeostasis.
Erion DM, Kotas ME, McGlashon J, Yonemitsu S, Hsiao JJ, Nagai Y, Iwasaki T, Murray SF, Bhanot S, Cline GW, Samuel VT, Shulman GI, Gillum MP. Erion DM, et al. Among authors: hsiao jj. J Biol Chem. 2013 May 31;288(22):16167-76. doi: 10.1074/jbc.M113.460246. Epub 2013 Apr 17. J Biol Chem. 2013. PMID: 23595987 Free PMC article.
SirT1 regulates adipose tissue inflammation.
Gillum MP, Kotas ME, Erion DM, Kursawe R, Chatterjee P, Nead KT, Muise ES, Hsiao JJ, Frederick DW, Yonemitsu S, Banks AS, Qiang L, Bhanot S, Olefsky JM, Sears DD, Caprio S, Shulman GI. Gillum MP, et al. Among authors: hsiao jj. Diabetes. 2011 Dec;60(12):3235-45. doi: 10.2337/db11-0616. Diabetes. 2011. PMID: 22110092 Free PMC article.
Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice.
Birkenfeld AL, Lee HY, Guebre-Egziabher F, Alves TC, Jurczak MJ, Jornayvaz FR, Zhang D, Hsiao JJ, Martin-Montalvo A, Fischer-Rosinsky A, Spranger J, Pfeiffer AF, Jordan J, Fromm MF, König J, Lieske S, Carmean CM, Frederick DW, Weismann D, Knauf F, Irusta PM, De Cabo R, Helfand SL, Samuel VT, Shulman GI. Birkenfeld AL, et al. Among authors: hsiao jj. Cell Metab. 2011 Aug 3;14(2):184-95. doi: 10.1016/j.cmet.2011.06.009. Cell Metab. 2011. PMID: 21803289 Free PMC article.
NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism.
Allouche J, Rachmin I, Adhikari K, Pardo LM, Lee JH, McConnell AM, Kato S, Fan S, Kawakami A, Suita Y, Wakamatsu K, Igras V, Zhang J, Navarro PP, Lugo CM, Noonan HR, Christie KA, Itin K, Mujahid N, Lo JA, Won CH, Evans CL, Weng QY, Wang H, Osseiran S, Lovas A, Németh I, Cozzio A, Navarini AA, Hsiao JJ, Nguyen N, Kemény LV, Iliopoulos O, Berking C, Ruzicka T, Gonzalez-José R, Bortolini MC, Canizales-Quinteros S, Acuna-Alonso V, Gallo C, Poletti G, Bedoya G, Rothhammer F, Ito S, Schiaffino MV, Chao LH, Kleinstiver BP, Tishkoff S, Zon LI, Nijsten T, Ruiz-Linares A, Fisher DE, Roider E. Allouche J, et al. Among authors: hsiao jj. Cell. 2021 Aug 5;184(16):4268-4283.e20. doi: 10.1016/j.cell.2021.06.022. Epub 2021 Jul 6. Cell. 2021. PMID: 34233163 Free PMC article.
42 results