Loeffler JP - Search Results

1

A ruthenium-containing organometallic compound reduces tumor growth through induction of the endoplasmic reticulum stress gene CHOP.

Meng X, Leyva ML, Jenny M, Gross I, Benosman S, Fricker B, Harlepp S, Hébraud P, Boos A, Wlosik P, Bischoff P, Sirlin C, Pfeffer M, Loeffler JP, Gaiddon C. Meng X, et al. Among authors: loeffler jp. Cancer Res. 2009 Jul 1;69(13):5458-66. doi: 10.1158/0008-5472.CAN-08-4408. Epub 2009 Jun 23. Cancer Res. 2009. PMID: 19549908

2

Ruthenium (II)-derived organometallic compounds induce cytostatic and cytotoxic effects on mammalian cancer cell lines through p53-dependent and p53-independent mechanisms.

Gaiddon C, Jeannequin P, Bischoff P, Pfeffer M, Sirlin C, Loeffler JP. Gaiddon C, et al. Among authors: loeffler jp. J Pharmacol Exp Ther. 2005 Dec;315(3):1403-11. doi: 10.1124/jpet.105.089342. Epub 2005 Sep 16. J Pharmacol Exp Ther. 2005. PMID: 16169939

3

Induction of caspase 8 and reactive oxygen species by ruthenium-derived anticancer compounds with improved water solubility and cytotoxicity.

Vidimar V, Meng X, Klajner M, Licona C, Fetzer L, Harlepp S, Hébraud P, Sidhoum M, Sirlin C, Loeffler JP, Mellitzer G, Sava G, Pfeffer M, Gaiddon C. Vidimar V, et al. Among authors: loeffler jp. Biochem Pharmacol. 2012 Dec 1;84(11):1428-36. doi: 10.1016/j.bcp.2012.08.022. Epub 2012 Sep 1. Biochem Pharmacol. 2012. PMID: 22964219

4

Complex regulation of p73 isoforms after alteration of amyloid precursor polypeptide (APP) function and DNA damage in neurons.

Benosman S, Meng X, Von Grabowiecki Y, Palamiuc L, Hritcu L, Gross I, Mellitzer G, Taya Y, Loeffler JP, Gaiddon C. Benosman S, et al. Among authors: loeffler jp. J Biol Chem. 2011 Dec 16;286(50):43013-25. doi: 10.1074/jbc.M111.261271. Epub 2011 Oct 14. J Biol Chem. 2011. PMID: 22002055 Free PMC article.

5

Cyclin-dependent kinases phosphorylate p73 at threonine 86 in a cell cycle-dependent manner and negatively regulate p73.

Gaiddon C, Lokshin M, Gross I, Levasseur D, Taya Y, Loeffler JP, Prives C. Gaiddon C, et al. Among authors: loeffler jp. J Biol Chem. 2003 Jul 25;278(30):27421-31. doi: 10.1074/jbc.M300251200. Epub 2003 Apr 3. J Biol Chem. 2003. PMID: 12676926 Free article.

6

Increased peripheral lipid clearance in an animal model of amyotrophic lateral sclerosis.

Fergani A, Oudart H, Gonzalez De Aguilar JL, Fricker B, René F, Hocquette JF, Meininger V, Dupuis L, Loeffler JP. Fergani A, et al. Among authors: loeffler jp. J Lipid Res. 2007 Jul;48(7):1571-80. doi: 10.1194/jlr.M700017-JLR200. Epub 2007 Apr 16. J Lipid Res. 2007. PMID: 17438338 Free PMC article.

7

Oxidative stress in skeletal muscle stimulates early expression of Rad in a mouse model of amyotrophic lateral sclerosis.

Halter B, Gonzalez de Aguilar JL, Rene F, Petri S, Fricker B, Echaniz-Laguna A, Dupuis L, Larmet Y, Loeffler JP. Halter B, et al. Among authors: loeffler jp. Free Radic Biol Med. 2010 Apr 1;48(7):915-23. doi: 10.1016/j.freeradbiomed.2010.01.014. Epub 2010 Jan 14. Free Radic Biol Med. 2010. PMID: 20079427

8

Brain-derived neurotrophic factor stimulates AP-1 and cyclic AMP-responsive element dependent transcriptional activity in central nervous system neurons.

Gaiddon C, Loeffler JP, Larmet Y. Gaiddon C, et al. Among authors: loeffler jp. J Neurochem. 1996 Jun;66(6):2279-86. doi: 10.1046/j.1471-4159.1996.66062279.x. J Neurochem. 1996. PMID: 8632149

9

The tissue-specific transcription factor Pit-1/GHF-1 binds to the c-fos serum response element and activates c-fos transcription.

Gaiddon C, de Tapia M, Loeffler JP. Gaiddon C, et al. Among authors: loeffler jp. Mol Endocrinol. 1999 May;13(5):742-51. doi: 10.1210/mend.13.5.0275. Mol Endocrinol. 1999. PMID: 10319324

10

Ca2+/calmodulin kinase types II and IV regulate c-fos transcription in the AtT20 corticotroph cell line.

Antoine M, Gaiddon C, Loeffler JP. Antoine M, et al. Among authors: loeffler jp. Mol Cell Endocrinol. 1996 Jun 18;120(1):1-8. doi: 10.1016/0303-7207(96)03806-3. Mol Cell Endocrinol. 1996. PMID: 8809732

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