Saldanha SA - Search Results

1

Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries.

Minond D, Saldanha SA, Subramaniam P, Spaargaren M, Spicer T, Fotsing JR, Weide T, Fokin VV, Sharpless KB, Galleni M, Bebrone C, Lassaux P, Hodder P. Minond D, et al. Among authors: saldanha sa. Bioorg Med Chem. 2009 Jul 15;17(14):5027-37. doi: 10.1016/j.bmc.2009.05.070. Epub 2009 Jun 22. Bioorg Med Chem. 2009. PMID: 19553129 Free PMC article.

2

High throughput screening of potentially selective MMP-13 exosite inhibitors utilizing a triple-helical FRET substrate.

Lauer-Fields JL, Minond D, Chase PS, Baillargeon PE, Saldanha SA, Stawikowska R, Hodder P, Fields GB. Lauer-Fields JL, et al. Among authors: saldanha sa. Bioorg Med Chem. 2009 Feb 1;17(3):990-1005. doi: 10.1016/j.bmc.2008.03.004. Epub 2008 Mar 6. Bioorg Med Chem. 2009. PMID: 18358729 Free PMC article.

3

NH-1,2,3-Triazole-based Inhibitors of the VIM-2 Metallo-β-Lactamase: Synthesis and Structure-Activity Studies.

Weide T, Saldanha SA, Minond D, Spicer TP, Fotsing JR, Spaargaren M, Frère JM, Bebrone C, Sharpless KB, Hodder PS, Fokin VV. Weide T, et al. Among authors: saldanha sa. ACS Med Chem Lett. 2010 Jul 8;1(4):150-154. doi: 10.1021/ml900022q. ACS Med Chem Lett. 2010. PMID: 20625539 Free PMC article.

4

Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole-cell high-throughput screening.

Brothers SP, Saldanha SA, Spicer TP, Cameron M, Mercer BA, Chase P, McDonald P, Wahlestedt C, Hodder PS. Brothers SP, et al. Among authors: saldanha sa. Mol Pharmacol. 2010 Jan;77(1):46-57. doi: 10.1124/mol.109.058677. Epub 2009 Oct 16. Mol Pharmacol. 2010. PMID: 19837904 Free PMC article.

5

Design, synthesis and SAR analysis of novel potent and selective small molecule antagonists of NPBWR1 (GPR7).

Urbano M, Guerrero M, Zhao J, Velaparthi S, Saldanha SA, Chase P, Wang Z, Civelli O, Hodder P, Schaeffer MT, Brown S, Rosen H, Roberts E. Urbano M, et al. Among authors: saldanha sa. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7135-41. doi: 10.1016/j.bmcl.2012.09.074. Epub 2012 Oct 2. Bioorg Med Chem Lett. 2012. PMID: 23079522 Free PMC article.

6

Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease.

Jacobs J, Grum-Tokars V, Zhou Y, Turlington M, Saldanha SA, Chase P, Eggler A, Dawson ES, Baez-Santos YM, Tomar S, Mielech AM, Baker SC, Lindsley CW, Hodder P, Mesecar A, Stauffer SR. Jacobs J, et al. Among authors: saldanha sa. J Med Chem. 2013 Jan 24;56(2):534-46. doi: 10.1021/jm301580n. Epub 2013 Jan 3. J Med Chem. 2013. PMID: 23231439 Free PMC article.

7

An Ultra-High-Throughput Screen for Catalytic Inhibitors of Serine/Threonine Protein Phosphatases Types 1 and 5 (PP1C and PP5C).

Swingle M, Volmar CH, Saldanha SA, Chase P, Eberhart C, Salter EA, D'Arcy B, Schroeder CE, Golden JE, Wierzbicki A, Hodder P, Honkanen RE. Swingle M, et al. Among authors: saldanha sa. SLAS Discov. 2017 Jan;22(1):21-31. doi: 10.1177/1087057116668852. Epub 2016 Sep 27. SLAS Discov. 2017. PMID: 27628691 Free PMC article.

8

Small-molecule inhibitors of acetyltransferase p300 identified by high-throughput screening are potent anticancer agents.

Yang H, Pinello CE, Luo J, Li D, Wang Y, Zhao LY, Jahn SC, Saldanha SA, Chase P, Planck J, Geary KR, Ma H, Law BK, Roush WR, Hodder P, Liao D. Yang H, et al. Among authors: saldanha sa. Mol Cancer Ther. 2013 May;12(5):610-20. doi: 10.1158/1535-7163.MCT-12-0930. Epub 2013 Apr 26. Mol Cancer Ther. 2013. PMID: 23625935 Free PMC article.

9

Small molecule activators of TRPML3.

Grimm C, Jörs S, Saldanha SA, Obukhov AG, Pan B, Oshima K, Cuajungco MP, Chase P, Hodder P, Heller S. Grimm C, et al. Among authors: saldanha sa. Chem Biol. 2010 Feb 26;17(2):135-48. doi: 10.1016/j.chembiol.2009.12.016. Chem Biol. 2010. PMID: 20189104 Free PMC article.

10

Identification of a μ-δ opioid receptor heteromer-biased agonist with antinociceptive activity.

Gomes I, Fujita W, Gupta A, Saldanha SA, Negri A, Pinello CE, Eberhart C, Roberts E, Filizola M, Hodder P, Devi LA. Gomes I, et al. Among authors: saldanha sa. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12072-7. doi: 10.1073/pnas.1222044110. Epub 2013 Jul 1. Proc Natl Acad Sci U S A. 2013. PMID: 23818586 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

44 results

Search Page

Filters