Colman PM - Search Results

1

Czabotar PE, Colman PM, Huang DC. Czabotar PE, et al. Among authors: colman pm. Cell Death Differ. 2009 Sep;16(9):1187-91. doi: 10.1038/cdd.2009.83. Epub 2009 Jun 26. Cell Death Differ. 2009. PMID: 19557009 Review.

2

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function.

Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG, Colman PM, Day CL, Adams JM, Huang DC. Chen L, et al. Among authors: colman pm. Mol Cell. 2005 Feb 4;17(3):393-403. doi: 10.1016/j.molcel.2004.12.030. Mol Cell. 2005. PMID: 15694340 Free article.

3

CED-4 forms a 2 : 2 heterotetrameric complex with CED-9 until specifically displaced by EGL-1 or CED-13.

Fairlie WD, Perugini MA, Kvansakul M, Chen L, Huang DC, Colman PM. Fairlie WD, et al. Among authors: colman pm. Cell Death Differ. 2006 Mar;13(3):426-34. doi: 10.1038/sj.cdd.4401762. Cell Death Differ. 2006. PMID: 16167070

4

Subversion of the Bcl-2 life/death switch in cancer development and therapy.

Adams JM, Huang DC, Strasser A, Willis S, Chen L, Wei A, van Delft M, Fletcher JI, Puthalakath H, Kuroda J, Michalak EM, Kelly PN, Bouillet P, Villunger A, O'Reilly L, Bath ML, Smith DP, Egle A, Harris AW, Hinds M, Colman P, Cory S. Adams JM, et al. Cold Spring Harb Symp Quant Biol. 2005;70:469-77. doi: 10.1101/sqb.2005.70.009. Cold Spring Harb Symp Quant Biol. 2005. PMID: 16869785

5

A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak.

Kvansakul M, van Delft MF, Lee EF, Gulbis JM, Fairlie WD, Huang DC, Colman PM. Kvansakul M, et al. Among authors: colman pm. Mol Cell. 2007 Mar 23;25(6):933-42. doi: 10.1016/j.molcel.2007.02.004. Mol Cell. 2007. PMID: 17386268 Free article.

6

Structural insights into the degradation of Mcl-1 induced by BH3 domains.

Czabotar PE, Lee EF, van Delft MF, Day CL, Smith BJ, Huang DC, Fairlie WD, Hinds MG, Colman PM. Czabotar PE, et al. Among authors: colman pm. Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6217-22. doi: 10.1073/pnas.0701297104. Epub 2007 Mar 27. Proc Natl Acad Sci U S A. 2007. PMID: 17389404 Free PMC article.

7

Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family.

Lee EF, Czabotar PE, Smith BJ, Deshayes K, Zobel K, Colman PM, Fairlie WD. Lee EF, et al. Among authors: colman pm. Cell Death Differ. 2007 Sep;14(9):1711-3. doi: 10.1038/sj.cdd.4402178. Epub 2007 Jun 15. Cell Death Differ. 2007. PMID: 17572662 No abstract available.

8

A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation.

Lee EF, Czabotar PE, van Delft MF, Michalak EM, Boyle MJ, Willis SN, Puthalakath H, Bouillet P, Colman PM, Huang DC, Fairlie WD. Lee EF, et al. Among authors: colman pm. J Cell Biol. 2008 Jan 28;180(2):341-55. doi: 10.1083/jcb.200708096. Epub 2008 Jan 21. J Cell Biol. 2008. PMID: 18209102 Free PMC article.

9

To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions.

Dewson G, Kratina T, Sim HW, Puthalakath H, Adams JM, Colman PM, Kluck RM. Dewson G, et al. Among authors: colman pm. Mol Cell. 2008 May 9;30(3):369-80. doi: 10.1016/j.molcel.2008.04.005. Mol Cell. 2008. PMID: 18471982 Free article.

10

Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands.

Kvansakul M, Yang H, Fairlie WD, Czabotar PE, Fischer SF, Perugini MA, Huang DC, Colman PM. Kvansakul M, et al. Among authors: colman pm. Cell Death Differ. 2008 Oct;15(10):1564-71. doi: 10.1038/cdd.2008.83. Epub 2008 Jun 13. Cell Death Differ. 2008. PMID: 18551131

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