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Page 1
Discovery of GSK1070916, a potent and selective inhibitor of Aurora B/C kinase.
Adams ND, Adams JL, Burgess JL, Chaudhari AM, Copeland RA, Donatelli CA, Drewry DH, Fisher KE, Hamajima T, Hardwicke MA, Huffman WF, Koretke-Brown KK, Lai ZV, McDonald OB, Nakamura H, Newlander KA, Oleykowski CA, Parrish CA, Patrick DR, Plant R, Sarpong MA, Sasaki K, Schmidt SJ, Silva DJ, Sutton D, Tang J, Thompson CS, Tummino PJ, Wang JC, Xiang H, Yang J, Dhanak D. Adams ND, et al. Among authors: adams jl. J Med Chem. 2010 May 27;53(10):3973-4001. doi: 10.1021/jm901870q. J Med Chem. 2010. PMID: 20420387
Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885.
King AJ, Patrick DR, Batorsky RS, Ho ML, Do HT, Zhang SY, Kumar R, Rusnak DW, Takle AK, Wilson DM, Hugger E, Wang L, Karreth F, Lougheed JC, Lee J, Chau D, Stout TJ, May EW, Rominger CM, Schaber MD, Luo L, Lakdawala AS, Adams JL, Contractor RG, Smalley KS, Herlyn M, Morrissey MM, Tuveson DA, Huang PS. King AJ, et al. Among authors: adams jl. Cancer Res. 2006 Dec 1;66(23):11100-5. doi: 10.1158/0008-5472.CAN-06-2554. Cancer Res. 2006. PMID: 17145850
Pyridinylimidazole inhibitors of Tie2 kinase.
Semones M, Feng Y, Johnson N, Adams JL, Winkler J, Hansbury M. Semones M, et al. Among authors: adams jl. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4756-60. doi: 10.1016/j.bmcl.2007.06.068. Epub 2007 Jun 27. Bioorg Med Chem Lett. 2007. PMID: 17618114
Inhibition of p38 MAP kinase as a therapeutic strategy.
Lee JC, Kumar S, Griswold DE, Underwood DC, Votta BJ, Adams JL. Lee JC, et al. Among authors: adams jl. Immunopharmacology. 2000 May;47(2-3):185-201. doi: 10.1016/s0162-3109(00)00206-x. Immunopharmacology. 2000. PMID: 10878289 Review.
350 results