A peptide-centric local stability assay enables proteome-scale identification of the protein targets and binding regions of diverse ligands.
Li K, Chen S, Wang K, Wang Y, Xue L, Ye Y, Fang Z, Lyu J, Zhu H, Li Y, Yu T, Yang F, Zhang X, Guo S, Ruan C, Zhou J, Wang Q, Dong M, Luo C, Ye M.
Li K, et al. Among authors: chen s.
Nat Methods. 2024 Dec 10. doi: 10.1038/s41592-024-02553-7. Online ahead of print.
Nat Methods. 2024.
PMID: 39658593