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HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo.
Dai Y, Yang Y, MacLeod V, Yue X, Rapraeger AC, Shriver Z, Venkataraman G, Sasisekharan R, Sanderson RD. Dai Y, et al. Among authors: yang y. J Biol Chem. 2005 Dec 2;280(48):40066-73. doi: 10.1074/jbc.M508136200. Epub 2005 Sep 27. J Biol Chem. 2005. PMID: 16192265 Free article.
The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy.
Yang Y, MacLeod V, Dai Y, Khotskaya-Sample Y, Shriver Z, Venkataraman G, Sasisekharan R, Naggi A, Torri G, Casu B, Vlodavsky I, Suva LJ, Epstein J, Yaccoby S, Shaughnessy JD Jr, Barlogie B, Sanderson RD. Yang Y, et al. Blood. 2007 Sep 15;110(6):2041-8. doi: 10.1182/blood-2007-04-082495. Epub 2007 May 29. Blood. 2007. PMID: 17536013 Free PMC article.
Syndecan-1: a dynamic regulator of the myeloma microenvironment.
Sanderson RD, Yang Y. Sanderson RD, et al. Among authors: yang y. Clin Exp Metastasis. 2008;25(2):149-59. doi: 10.1007/s10585-007-9125-3. Epub 2007 Nov 20. Clin Exp Metastasis. 2008. PMID: 18027090 Free PMC article. Review.
SST0001, a chemically modified heparin, inhibits myeloma growth and angiogenesis via disruption of the heparanase/syndecan-1 axis.
Ritchie JP, Ramani VC, Ren Y, Naggi A, Torri G, Casu B, Penco S, Pisano C, Carminati P, Tortoreto M, Zunino F, Vlodavsky I, Sanderson RD, Yang Y. Ritchie JP, et al. Among authors: yang y. Clin Cancer Res. 2011 Mar 15;17(6):1382-93. doi: 10.1158/1078-0432.CCR-10-2476. Epub 2011 Jan 21. Clin Cancer Res. 2011. PMID: 21257720 Free PMC article.
109,153 results
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