Chiga M - Search Results

1

Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure.

Ohta A, Rai T, Yui N, Chiga M, Yang SS, Lin SH, Sohara E, Sasaki S, Uchida S. Ohta A, et al. Among authors: chiga m. Hum Mol Genet. 2009 Oct 15;18(20):3978-86. doi: 10.1093/hmg/ddp344. Epub 2009 Jul 24. Hum Mol Genet. 2009. PMID: 19633012

2

Overexpression of human WNK1 increases paracellular chloride permeability and phosphorylation of claudin-4 in MDCKII cells.

Ohta A, Yang SS, Rai T, Chiga M, Sasaki S, Uchida S. Ohta A, et al. Among authors: chiga m. Biochem Biophys Res Commun. 2006 Oct 20;349(2):804-8. doi: 10.1016/j.bbrc.2006.08.101. Epub 2006 Aug 24. Biochem Biophys Res Commun. 2006. PMID: 16949040

3

Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model.

Yang SS, Morimoto T, Rai T, Chiga M, Sohara E, Ohno M, Uchida K, Lin SH, Moriguchi T, Shibuya H, Kondo Y, Sasaki S, Uchida S. Yang SS, et al. Among authors: chiga m. Cell Metab. 2007 May;5(5):331-44. doi: 10.1016/j.cmet.2007.03.009. Cell Metab. 2007. PMID: 17488636 Free article.

4

Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone.

Chiga M, Rai T, Yang SS, Ohta A, Takizawa T, Sasaki S, Uchida S. Chiga M, et al. Kidney Int. 2008 Dec;74(11):1403-9. doi: 10.1038/ki.2008.451. Epub 2008 Sep 17. Kidney Int. 2008. PMID: 18800028 Free article.

5

Mechanisms for hypercalciuria in pseudohypoaldosteronism type II-causing WNK4 knock-in mice.

Yang SS, Hsu YJ, Chiga M, Rai T, Sasaki S, Uchida S, Lin SH. Yang SS, et al. Among authors: chiga m. Endocrinology. 2010 Apr;151(4):1829-36. doi: 10.1210/en.2009-0951. Epub 2010 Feb 24. Endocrinology. 2010. PMID: 20181799

6

Phenotypes of pseudohypoaldosteronism type II caused by the WNK4 D561A missense mutation are dependent on the WNK-OSR1/SPAK kinase cascade.

Chiga M, Rafiqi FH, Alessi DR, Sohara E, Ohta A, Rai T, Sasaki S, Uchida S. Chiga M, et al. J Cell Sci. 2011 May 1;124(Pt 9):1391-5. doi: 10.1242/jcs.084111. Epub 2011 Apr 12. J Cell Sci. 2011. PMID: 21486947

7

Immunolocalization of WNK4 in mouse kidney.

Ohno M, Uchida K, Ohashi T, Nitta K, Ohta A, Chiga M, Sasaki S, Uchida S. Ohno M, et al. Among authors: chiga m. Histochem Cell Biol. 2011 Jul;136(1):25-35. doi: 10.1007/s00418-011-0827-x. Epub 2011 Jun 10. Histochem Cell Biol. 2011. PMID: 21660484

8

Acute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidney.

Sohara E, Rai T, Yang SS, Ohta A, Naito S, Chiga M, Nomura N, Lin SH, Vandewalle A, Ohta E, Sasaki S, Uchida S. Sohara E, et al. Among authors: chiga m. PLoS One. 2011;6(8):e24277. doi: 10.1371/journal.pone.0024277. Epub 2011 Aug 31. PLoS One. 2011. PMID: 21909387 Free PMC article.

9

Phosphorylation of Na-Cl cotransporter by OSR1 and SPAK kinases regulates its ubiquitination.

Hossain Khan MZ, Sohara E, Ohta A, Chiga M, Inoue Y, Isobe K, Wakabayashi M, Oi K, Rai T, Sasaki S, Uchida S. Hossain Khan MZ, et al. Among authors: chiga m. Biochem Biophys Res Commun. 2012 Aug 24;425(2):456-61. doi: 10.1016/j.bbrc.2012.07.124. Epub 2012 Jul 27. Biochem Biophys Res Commun. 2012. PMID: 22846565

10

Phosphatidylinositol 3-kinase/Akt signaling pathway activates the WNK-OSR1/SPAK-NCC phosphorylation cascade in hyperinsulinemic db/db mice.

Nishida H, Sohara E, Nomura N, Chiga M, Alessi DR, Rai T, Sasaki S, Uchida S. Nishida H, et al. Among authors: chiga m. Hypertension. 2012 Oct;60(4):981-90. doi: 10.1161/HYPERTENSIONAHA.112.201509. Epub 2012 Sep 4. Hypertension. 2012. PMID: 22949526 Free PMC article.

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