Hanessian S - Search Results

1

From natural products to achiral drug prototypes: potent thrombin inhibitors based on P2/P3 dihydropyrid-2-one core motifs.

Hanessian S, Therrien E, Zhang J, Otterlo Wv, Xue Y, Gustafsson D, Nilsson I, Fjellström O. Hanessian S, et al. Bioorg Med Chem Lett. 2009 Sep 15;19(18):5429-32. doi: 10.1016/j.bmcl.2009.07.107. Epub 2009 Jul 26. Bioorg Med Chem Lett. 2009. PMID: 19674897

2

Probing the importance of spacial and conformational domains in captopril analogs for angiotensin converting enzyme activity.

Hanessian S, Reinhold U, Saulnier M, Claridge S. Hanessian S, et al. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2123-8. doi: 10.1016/s0960-894x(98)00377-1. Bioorg Med Chem Lett. 1998. PMID: 9873498

3

Exploration of beta-turn scaffolding motifs as components of sialyl Le(X) mimetics and their relevance to P-selectin.

Hanessian S, Huynh HK, Reddy GV, McNaughton-Smith G, Ernst B, Kolb HC, Magnani J, Sweeley C. Hanessian S, et al. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2803-8. doi: 10.1016/s0960-894x(98)00500-9. Bioorg Med Chem Lett. 1998. PMID: 9873626

4

Asymmetric synthesis of L-azetidine-2-carboxylic acid and 3-substituted congeners--conformationally constrained analogs of phenylalanine, naphthylalanine, and leucine.

Hanessian S, Bernstein N, Yang RY, Maguire R. Hanessian S, et al. Bioorg Med Chem Lett. 1999 May 17;9(10):1437-42. doi: 10.1016/s0960-894x(99)00218-8. Bioorg Med Chem Lett. 1999. PMID: 10360752

5

Picking the S1, S1' and S2' pockets of matrix metalloproteinases. A niche for potent acyclic sulfonamide inhibitors.

Hanessian S, Bouzbouz S, Boudon A, Tucker GC, Peyroulan D. Hanessian S, et al. Bioorg Med Chem Lett. 1999 Jun 21;9(12):1691-6. doi: 10.1016/s0960-894x(99)00259-0. Bioorg Med Chem Lett. 1999. PMID: 10397503

6

Synthesis of a phostone glycomimetic of the endothelin converting enzyme inhibitor phosphoramidon.

Hanessian S, Rogel O. Hanessian S, et al. Bioorg Med Chem Lett. 1999 Aug 16;9(16):2441-6. doi: 10.1016/s0960-894x(99)00401-1. Bioorg Med Chem Lett. 1999. PMID: 10476884

7

Exploring the chiral space within the active site of alpha-thrombin with a constrained mimic of D-Phe-Pro-Arg--design, synthesis, inhibitory activity, and X-ray structure of an enzyme-inhibitor complex.

Hanessian S, Balaux E, Musil D, Olsson LL, Nilsson I. Hanessian S, et al. Bioorg Med Chem Lett. 2000 Feb 7;10(3):243-7. doi: 10.1016/s0960-894x(99)00669-1. Bioorg Med Chem Lett. 2000. PMID: 10698445

8

Design and synthesis of mimics of S-adenosyl-L-homocysteine as potential inhibitors of erythromycin methyltransferases.

Hanessian S, Sgarbi PW. Hanessian S, et al. Bioorg Med Chem Lett. 2000 Mar 6;10(5):433-7. doi: 10.1016/s0960-894x(00)00021-4. Bioorg Med Chem Lett. 2000. PMID: 10743942

9

Design and synthesis of functionalized glycomers as non-peptidic ligands for SH2 binding and as inhibitors of A-431 human epidermoid and HT-29 colon carcinoma cell lines.

Hanessian S, Saavedra OM, Xie F, Amboldi N, Battistini C. Hanessian S, et al. Bioorg Med Chem Lett. 2000 Mar 6;10(5):439-42. doi: 10.1016/s0960-894x(00)00022-6. Bioorg Med Chem Lett. 2000. PMID: 10743943

10

N-Aryl sulfonyl homocysteine hydroxamate inhibitors of matrix metalloproteinases: further probing of the S(1), S(1)', and S(2)' pockets.

Hanessian S, Moitessier N, Gauchet C, Viau M. Hanessian S, et al. J Med Chem. 2001 Sep 13;44(19):3066-73. doi: 10.1021/jm010097f. J Med Chem. 2001. PMID: 11543675

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

204 results

Search Page

Filters